2023
Improvement in cardiac function and regional LV strain following intramyocardial injection of a theranostic hydrogel early postmyocardial infarction in a porcine model
Avendaño R, Midgett D, Melvinsdottir I, Thorn S, Uman S, Pickell Z, Lee S, Liu Z, Mamarian M, Duncan J, Spinale F, Burdick J, Sinusas A. Improvement in cardiac function and regional LV strain following intramyocardial injection of a theranostic hydrogel early postmyocardial infarction in a porcine model. Journal Of Applied Physiology 2023, 135: 405-420. PMID: 37318987, PMCID: PMC10538987, DOI: 10.1152/japplphysiol.00342.2022.Peer-Reviewed Original ResearchConceptsMyocardial infarctionIntramyocardial deliveryLV hemodynamicsControl groupFunctional indexEarly post-myocardial infarctionSystolic functional indicesMyocardial performance indexAnterolateral myocardial infarctionLeft anterior descendingPressure-volume loop areaLeft ventricular remodelingGlobal LV functionLV functional changesPost-myocardial infarctionSupply/demand ratioRegional LV strainHydrogel groupTei indexEjection fractionHeart failureAnterior descendingCircumflex arteryLV functionAortic pressure
2018
Prevention of sudden cardiac death in ischaemic cardiomyopathy
Romero J, Natale A, Avendano R, Garcia M, Biase L. Prevention of sudden cardiac death in ischaemic cardiomyopathy. 2018, 2333-2337. DOI: 10.1093/med/9780198784906.003.0552.Peer-Reviewed Original ResearchLeft ventricular ejection fractionSudden cardiac deathAcute myocardial infarctionRisk stratificationMyocardial infarctionElectrophysiological studiesCardiac deathIschemic cardiomyopathyPrevention of SCDCardiac iodine-123 metaiodobenzylguanidineIodine-123 metaiodobenzylguanidineTransient myocardial stunningCardiovascular magnetic resonance imagingVentricular ejection fractionPrimary prevention strategiesMajor health problemChronic myocardial infarctionImplantable cardioverter defibrillatorMagnetic resonance imagingEjection fractionVentricular arrhythmiasLVEF assessmentPrimary preventionMyocardial stunningCurrent guidelines