Bivalirudin versus heparin in patients undergoing percutaneous peripheral interventions: A systematic review and meta-analysis
Olmedo W, Villablanca P, Sanina C, Walker J, Weinreich M, Brevik J, Avendano R, Bravo C, Romero J, Ramakrishna H, Babaev A, Attubato M, Hernandez-Suarez D, Cox-Alomar P, Pyo R, Krishnan P, Wiley J. Bivalirudin versus heparin in patients undergoing percutaneous peripheral interventions: A systematic review and meta-analysis. Vascular 2018, 27: 78-89. PMID: 30501582, DOI: 10.1177/1708538118807522.Peer-Reviewed Original ResearchConceptsPercutaneous peripheral interventionsAccess site complicationsPeripheral interventionsCause mortalitySite complicationsMinor bleedingSystematic reviewEfficacy of bivalirudinProcedural anticoagulant agentLarge randomized trialsSignificant differencesBivalirudin useMajor bleedingIntracranial bleedingBlood transfusionRandomized trialsMyocardial infarctionAnticoagulant agentsClinical studiesBivalirudinBleedingComplicationsPatientsHeparinMortalityBenefit of left atrial appendage electrical isolation for persistent and long-standing persistent atrial fibrillation: a systematic review and meta-analysis
Romero J, Michaud G, Avendano R, Briceño D, Kumar S, Diaz J, Mohanty S, Trivedi C, Gianni C, Della Rocca D, Proietti R, Perrotta L, Bordignon S, Chun J, Schmidt B, Garcia M, Natale A, Di Biase L. Benefit of left atrial appendage electrical isolation for persistent and long-standing persistent atrial fibrillation: a systematic review and meta-analysis. EP Europace 2018, 20: 1268-1278. PMID: 29342299, DOI: 10.1093/europace/eux372.Peer-Reviewed Original ResearchConceptsAtrial appendage electrical isolationPersistent atrial fibrillationAtrial fibrillationIschemic strokeSystematic reviewNon-paroxysmal AF patientsStandard ablationNon-paroxysmal atrial fibrillationAcute procedural complicationsIncremental benefitAcute complication rateLong-term outcomesAntiarrhythmic medicationsArrhythmia recurrenceComplication rateAF patientsProcedural complicationsCatheter ablationAtrial arrhythmiasClinical studiesOverall freedomLAAEIPatientsLSPAFFibrillation