2024
Clinical Implications of Low Body Mass Index on Endovascular Lower Extremity Revascularization
Pinto Rodriguez P, Alameddine D, Huttler J, Damara F, Slade M, Cardella J, Guzman R, Chaar C. Clinical Implications of Low Body Mass Index on Endovascular Lower Extremity Revascularization. Annals Of Vascular Surgery 2024, 106: 350-359. PMID: 38810726, DOI: 10.1016/j.avsg.2024.02.031.Peer-Reviewed Original ResearchPeripheral vascular interventionsPeripheral arterial diseaseLower body mass indexUnderweight patientsLong-term outcomesBody mass indexNonobese patientsMass indexRetrospective analysis of patientsRate of thrombotic complicationsHigher 30-day mortalityRates of amputation-free survivalRate of reinterventionOutcomes of patientsPeripheral arterial disease patientsAnalysis of patientsKaplan-Meier analysisImpact of malnutritionBaseline demographic characteristicsChronic limb-threatening ischemiaEpidemic of obesityOptimization of nutritionLonger hospital lengthAdverse limb eventsAmputation-free survivalIntravascular Ultrasound Use is Associated with Improved Patency in Lower Extremity Peripheral Arterial Interventions
Brahmandam A, Kim T, Parziale S, Deng Y, Setia O, Tonnessen B, Ochoa Chaar C, Guzman R, Aboian E. Intravascular Ultrasound Use is Associated with Improved Patency in Lower Extremity Peripheral Arterial Interventions. Annals Of Vascular Surgery 2024, 106: 410-418. PMID: 38810722, DOI: 10.1016/j.avsg.2024.03.008.Peer-Reviewed Original ResearchChronic limb-threatening ischemiaChronic limb threatening ischemia patientsGeneralized estimating equationsPeripheral vascular interventionsPeripheral arterial diseaseAssociated with improved patencyPredictors of 1-year outcomeIntravascular ultrasound useVascular Quality InitiativeSubgroup analysisAdjunctive useD lesionsTASC CPropensity matchingTreatment modalitiesTrans-Atlantic Inter-Society Consensus (TASC) classificationMajor amputationLimb-threatening ischemiaBalloon angioplastyIntravascular ultrasoundImproved patencyUltrasound useOne-year followQuality InitiativePredictors of patencyClinician perspectives regarding CYP2C19 genotype testing in patients with critical limb ischemia: A Delphi approach.
Regan C, Scierka L, Dardik A, Tonnessen B, Iyad Ochoa Chaar C, Ionescu C, Aboian E, Cardella J, Nassiri N, Guzman R, Attaran R, Nagpal S, Shah S, Smolderen K, Mena-Hurtado C. Clinician perspectives regarding CYP2C19 genotype testing in patients with critical limb ischemia: A Delphi approach. Vascular 2024, 17085381241246318. PMID: 38669051, DOI: 10.1177/17085381241246318.Peer-Reviewed Original ResearchDual antiplatelet therapyPeripheral arterial diseaseCYP2C19 testingCYP2C19 mutationsHeterogeneity of treatment effectsPeripheral vascular interventionsConsensus statementKnowledge questionsAntiplatelet therapyGenetic testingVascular surgeryAcademic health systemBarriers to implementationInterquartile rangeCYP2C19 genotype testingVascular diseaseInterventional cardiologyModified Delphi methodPatient's metabolic statusManagement of patientsCritical limb ischemiaPerceived barriersPeripheral vascular diseaseArterial vascular diseaseClinician perspectivesAnticoagulation in Patients with Premature Peripheral Artery Disease Undergoing Lower Extremity Revascularization
Kim T, DeWan A, Murray M, Wang H, Mani A, Mena-Hurtado C, Guzman R, Ochoa Chaar C. Anticoagulation in Patients with Premature Peripheral Artery Disease Undergoing Lower Extremity Revascularization. Annals Of Vascular Surgery 2024, 105: 150-157. PMID: 38593922, DOI: 10.1016/j.avsg.2024.02.006.Peer-Reviewed Original ResearchPremature peripheral arterial diseaseAntiplatelet therapyVascular Quality InitiativeArtery diseaseAdjunct to antiplatelet therapyReturn to the operating roomPost-operative anticoagulationCompared to patientsPostoperative antiplatelet therapyOne-year outcomesCongestive heart failureLower extremity revascularizationMajor adverse limb eventsCoronary artery diseaseEffects of anticoagulantsAmputation-free survivalEarly onset of diseaseAdverse limb eventsPeripheral vascular interventionsOnset of diseasePeripheral arterial diseaseLower-extremity revascularizationPropensity score matchingPerioperative mortalityBaseline characteristics
2023
The Utilization of Protamine during Peripheral Vascular Interventions in the VQI
Ali S, Shebl F, Aboian E, Strosberg D, Fischer U, Cardella J, Guzman R, Ochoa Chaar C. The Utilization of Protamine during Peripheral Vascular Interventions in the VQI. Annals Of Vascular Surgery 2023, 101: 72-79. PMID: 38110083, DOI: 10.1016/j.avsg.2023.10.019.Peer-Reviewed Original ResearchPeripheral vascular interventionsAdjusted rate ratiosProtamine useCardiac complicationsPropensity matchingVascular interventionsChronic obstructive pulmonary diseasePropensity scoreCharacteristics of patientsPeripheral arterial diseaseCongestive heart failureObstructive pulmonary diseaseMultivariable Poisson regressionUse of protamineSignificant differencesMedical comorbiditiesP2Y12 inhibitorsPerioperative bleedingPerioperative medicationsPerioperative outcomesDistal embolizationPatient comorbiditiesCarotid surgeryHeart failurePulmonary disease