2018
Autologous iPSC-Based Vaccines Elicit Anti-tumor Responses In Vivo
Kooreman NG, Kim Y, de Almeida PE, Termglinchan V, Diecke S, Shao NY, Wei TT, Yi H, Dey D, Nelakanti R, Brouwer TP, Paik DT, Sagiv-Barfi I, Han A, Quax PHA, Hamming JF, Levy R, Davis MM, Wu JC. Autologous iPSC-Based Vaccines Elicit Anti-tumor Responses In Vivo. Cell Stem Cell 2018, 22: 501-513.e7. PMID: 29456158, PMCID: PMC6134179, DOI: 10.1016/j.stem.2018.01.016.Peer-Reviewed Original ResearchConceptsElicit anti-tumor responsesAnti-tumor responseInduced pluripotent stem cellsTumor growthMetastatic tumor loadTumor-associated antigensAnti-tumor vaccinesMurine breast cancerTumor-bearing miceAutologous induced pluripotent stem cellsUnvaccinated recipientsProphylactic settingAdoptive transferClinical immunotherapyCancer vaccinesTumor loadMelanoma recurrenceBreast cancerResection siteMelanoma modelMyeloid cellsCell responsesVaccineCancer cellsCancer
2015
Teratoma Formation: A Tool for Monitoring Pluripotency in Stem Cell Research
Nelakanti RV, Kooreman NG, Wu JC. Teratoma Formation: A Tool for Monitoring Pluripotency in Stem Cell Research. Current Protocols In Stem Cell Biology 2015, 32: 4a.8.1-4a.8.17. PMID: 25640819, PMCID: PMC4402211, DOI: 10.1002/9780470151808.sc04a08s32.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsEmbryonic germ layersInduced pluripotent stem cellsPluripotent stem cellsSpecific tissue typesStem cell researchGerm layersPluripotencyTeratoma formationTeratoma growthStem cellsTissue typesCell researchCell linesDetailed identificationMesodermCellsImmunodeficient miceProtocolGrowthLayerIdentification