2012
The neurobiology of schizotypy: Fronto-striatal prediction error signal correlates with delusion-like beliefs in healthy people
Corlett PR, Fletcher PC. The neurobiology of schizotypy: Fronto-striatal prediction error signal correlates with delusion-like beliefs in healthy people. Neuropsychologia 2012, 50: 3612-3620. PMID: 23079501, PMCID: PMC3694307, DOI: 10.1016/j.neuropsychologia.2012.09.045.Peer-Reviewed Original ResearchConceptsHealthy peopleSymptoms of psychosisPsychotic illnessEarly psychosisHealthy individualsPsychosis showHealthy beliefsAdditional alterationsNeural markersNeural responsesSymptomsPsychosisNovel evidenceDelusional ideationDistressSchizotypal experiencesAlterationsPatientsPrevious observationsIllness
2007
Predictive performance of the Domino, Hijazi, and Clements models during low-dose target-controlled ketamine infusions in healthy volunteers
Absalom A, Lee M, Menon D, Sharar S, De Smet T, Halliday J, Ogden M, Corlett P, Honey G, Fletcher P. Predictive performance of the Domino, Hijazi, and Clements models during low-dose target-controlled ketamine infusions in healthy volunteers. British Journal Of Anaesthesia 2007, 98: 615-623. PMID: 17389691, PMCID: PMC3838936, DOI: 10.1093/bja/aem063.Peer-Reviewed Original ResearchConceptsTarget-controlled infusionKetamine infusionHealthy volunteersLow-dose ketamine infusionPlasma concentration-time courseVenous blood samplesCognitive function testsConcentration-time courseFunction testsKetamine administrationTarget concentrationBlood samplesKetamine modelInfusionMore occasionsTCI deviceFunctional neuroimagingVolunteers