2025
Epistemic trust and social learning: a transdiagnostic integrative model of mental disorders and therapeutic interventions
Fonagy P, Campbell C, Allison E, Luyten P. Epistemic trust and social learning: a transdiagnostic integrative model of mental disorders and therapeutic interventions. 2025, 251-269. DOI: 10.4337/9781803929415.00027.Peer-Reviewed Original ResearchWirksamkeit eines mentalisierungsbasierten Trainings für Lehrkräfte und pädagogische Fachkräfte – Ergebnisse einer Pilotstudie
Schwarzer N, Behringer N, Dees P, Fonagy P, Gingelmaier S, Henter M, Hutsebaut J, Kirsch H, Kreuzer T, Langnickel R, Maier L, Müller S, Turner A, Link P, Nolte T. Wirksamkeit eines mentalisierungsbasierten Trainings für Lehrkräfte und pädagogische Fachkräfte – Ergebnisse einer Pilotstudie. Prävention Und Gesundheitsförderung 2025, 1-9. DOI: 10.1007/s11553-025-01209-4.Peer-Reviewed Original ResearchMental healthTraining programMental trainingMental training programSymptom distressPaired t-testMental abilityControl groupEpistemic trustQuality of teacher-student relationshipsSymptom ChecklistResultsThe treatment groupTeacher-student relationshipConclusionThe studyHealthEducation staffFunction QuestionnaireReflective Functioning QuestionnaireT-testParticipantsAttributional Complexity ScaleRegression analysisEnhancing teachersPedagogical interactionPedagogical workProtocol for the economic evaluation of group interpersonal therapy for postnatal depression compared with high-quality standard care in Kenya and Lebanon (SUMMIT trial)
Jaoude G, Madeghe B, Maradian S, Posbic P, Machoka J, Ndamaiyu G, Simes E, O’Donnell C, Wallace-Hanlon S, Evans R, Fearon P, Allison E, Pilling S, Verdeli L, Cheng B, Fouad F, Ngunu C, Chammay R, Kumar M, Fonagy P, Skordis J. Protocol for the economic evaluation of group interpersonal therapy for postnatal depression compared with high-quality standard care in Kenya and Lebanon (SUMMIT trial). NIHR Open Research 2025, 5: 17. DOI: 10.3310/nihropenres.13838.1.Peer-Reviewed Original ResearchInterpersonal therapyIncremental cost-effectiveness ratioChildren's cognitive developmentCognitive developmentPostnatal depressionEconomic evaluationUniversity College London Research Ethics CommitteeStandard careEstimate incremental cost-effectiveness ratiosLong-term depressionTrial outcomesPoor developmental outcomesPrimary trial outcomeDepression outcomesSecondary trial outcomesMaternal depressionPeer-reviewed journal publicationsControlled superiority trialImprove children's cognitive developmentResearch Ethics CommitteeKenyatta National HospitalQuality of lifeCost-effectiveness ratioIntention-to-treat analysisTrial follow-upMentalisation-based treatment for antisocial personality disorder in males convicted of an offence on community probation in England and Wales (Mentalization for Offending Adult Males, MOAM): a multicentre, assessor-blinded, randomised controlled trial
Fonagy P, Simes E, Yirmiya K, Wason J, Barrett B, Frater A, Cameron A, Butler S, Hoare Z, McMurran M, Moran P, Crawford M, Pilling S, Allison E, Yakeley J, Bateman A. Mentalisation-based treatment for antisocial personality disorder in males convicted of an offence on community probation in England and Wales (Mentalization for Offending Adult Males, MOAM): a multicentre, assessor-blinded, randomised controlled trial. The Lancet Psychiatry 2025, 12: 208-219. PMID: 39978982, DOI: 10.1016/s2215-0366(24)00445-0.Peer-Reviewed Original ResearchConceptsOvert Aggression Scale-ModifiedAntisocial personality disorderMentalisation-based treatmentPersonality disorderDSM-5 criteriaReducing aggressive behaviorService supervisionGroup therapy sessionsEffects of thoughtsCriminal justice systemForensic populationsTreatment gainsDSM-5Psychological treatmentPathway servicesTherapy sessionsAggressive behaviorIndividual sessionsJustice systemCommunity probationFollow-up timepointsUsual groupProbationFindings’ generalisability,Trial proceduresThe most important aims of psychotherapy: to love, to work, and to find meaning
Zavlis O, Fonagy P, Luyten P. The most important aims of psychotherapy: to love, to work, and to find meaning. The Lancet Psychiatry 2025, 12: 173-174. PMID: 39978979, DOI: 10.1016/s2215-0366(25)00006-9.Peer-Reviewed Original ResearchSpecial Section: Self–Other Distinction in Personality Disorders
De Meulemeester C, Luyten P, Fonagy P. Special Section: Self–Other Distinction in Personality Disorders. Personality Disorders Theory Research And Treatment 2025, 16: 103-109. PMID: 40029301, DOI: 10.1037/per0000716.Peer-Reviewed Original ResearchConceptsSelf-other distinctionPersonality disorderSocial neuroscienceExperimental psychologyFeatures of personality disordersSelf-otherPerspective-taking difficultiesSelf-other boundariesPersonality pathologySociocognitive capacitiesClinical psychologyInterpersonal functioningDimensional viewEmotional contagionPsychologyDisordersImpairmentCoordination difficultiesEffects of treatmentNeurosciencePersonsSpecial sectionSelfResearch traditionsIncreased insightThe experience and role of dissociation in psychosis following developmental trauma: A systematic review
Melegkovits E, Tang R, Pounds O, Ashcroft K, Jung P, Kennerley H, Fonagy P, Bloomfield M. The experience and role of dissociation in psychosis following developmental trauma: A systematic review. Clinical Psychology Review 2025, 117: 102564. PMID: 40058297, DOI: 10.1016/j.cpr.2025.102564.Peer-Reviewed Original ResearchDevelopmental traumaPositive psychotic symptomsAssociated with dissociationElevated dissociationDelusional ideationDissociative symptomsPsychotic featuresPsychotic symptomsPsychotic manifestationsPsychosisEmotional abuseModerate associationPre-registeredDose-response effectClinical considerationsAbuseGeneral populationElevated riskSymptomsSystematic reviewIdeationParanoiaHallucinationsRisk of biasIndividualsThe Impact of Place-Based Approaches Addressing Mental Health and Substance Use Among Adolescents: A Systematic Review of the Literature
Rehill N, Halvorsrud K, Shand J, Fonagy P, Raine R. The Impact of Place-Based Approaches Addressing Mental Health and Substance Use Among Adolescents: A Systematic Review of the Literature. Public Health Reviews 2025, 45: 1607955. PMID: 40027468, PMCID: PMC11867790, DOI: 10.3389/phrs.2024.1607955.Peer-Reviewed Original ResearchPlace-based approachMental health outcomesMental healthHealth outcomesSubstance useYoung peopleComplex health challengesMulti-sectoral actionHigher quality evaluationsPeer-reviewed evidenceAssessed study qualityAlcohol use outcomesStudy qualityHealth challengesStudy designSubstance-useSystematic reviewBinge-drinkingHealthDrug useMeta-analysisDelayed initiationWellbeingAdolescentsPublished studiesBridging the Gap: A Qualitative Study Exploring the Impact of the Involvement of Researchers With Lived Experience on a Multisite Randomised Control Trial in the National Probation Service in England and Wales
Simes E, Butler S, Allison E, Barrett B, Bateman A, Cameron A, Crawford M, Frater A, Hoare Z, McMurran M, Moran P, Pilling S, Wason J, Yakeley J, Fonagy P. Bridging the Gap: A Qualitative Study Exploring the Impact of the Involvement of Researchers With Lived Experience on a Multisite Randomised Control Trial in the National Probation Service in England and Wales. Health Expectations 2025, 28: e70162. PMID: 39902497, PMCID: PMC11791406, DOI: 10.1111/hex.70162.Peer-Reviewed Original ResearchConceptsNational Probation ServiceCriminal justice systemProbation serviceCommunity sentencesJustice systemEngagement barriersQualitative studyEx-offendersTrial participantsMultisite randomised controlled trialInvolvement of individualsAdequate clinical supervisionKnowledge generationSemi-structured interviewsData collectorsService user organisationsRandomised controlled trialsEthical argumentsLived experienceInvolvement of researchersPrisonInterview scheduleMultisite RCTDissemination planClinical supervisionOpen Access: Addressing dissociation symptoms with trauma-focused mentalization-based treatment
Rüfenacht E, Shaverin L, Stubley J, Smits M, Bateman A, Fonagy P, Luyten P. Open Access: Addressing dissociation symptoms with trauma-focused mentalization-based treatment. 2025, 173-197. DOI: 10.4324/9781003560616-8.Peer-Reviewed Original ResearchMentalization-based treatmentDissociative symptomsHistory of traumatic experiencesPost-traumatic stress symptomsExpressions of dissociationMental health careMentalization theoryStress symptomsTraumatic experiencesTreatment approachesSymptomsMentalTherapeutic objectivesHealth careClinical settingClinical symptomsAttachmentDissociationIntranasal oxytocin increases breast milk oxytocin, but has a reduced effect in depressed mothers: A randomized controlled trialcon
Lindley Baron-Cohen K, Fearon P, Feldman R, Hardiman P, Zagoory-Sharon O, Meins E, Fonagy P. Intranasal oxytocin increases breast milk oxytocin, but has a reduced effect in depressed mothers: A randomized controlled trialcon. Psychoneuroendocrinology 2025, 174: 107374. PMID: 39891981, DOI: 10.1016/j.psyneuen.2025.107374.Peer-Reviewed Original ResearchConceptsEdinburgh Postnatal Depression ScaleBreast milkPostnatal depressionSymptoms of postnatal depressionAdministration of exogenous OTOT concentrationsCut-off pointRandomized controlled trialsPostnatal Depression ScalePostnatal depressive symptomsDouble-blindNasal sprayMother-infant bondingPotential biological mechanismsMaternal postnatal depressionOT contentBreast milk samplesMental health vulnerabilitiesOT pathwaysExogenous OTOT administrationControl mothersBreastDepressed mothersOxytocinSystematic Review and Individual Participant Data Meta-Analysis: Reducing Self-Harm in Adolescents: Pooled Treatment Effects, Study, Treatment and Participant Moderators
Wright-Hughes A, Farrin A, Fonagy P, Ougrin D, Stahl D, Wright J, Irving D, Mughal F, Truscott A, Diggins E, Chanen A, Cooney E, Carter G, Clover K, Dadds M, Diamond G, Esposito-Smythers C, Green J, Griffiths H, Hassanian-Moghaddam H, Hatcher S, Hazell P, Husein N, Kaess M, King C, Morthorst B, O'Connor R, Santamarina-Perez P, Tyrer P, Walwyn R, Cottrell D. Systematic Review and Individual Participant Data Meta-Analysis: Reducing Self-Harm in Adolescents: Pooled Treatment Effects, Study, Treatment and Participant Moderators. Journal Of The American Academy Of Child & Adolescent Psychiatry 2025 PMID: 39892472, DOI: 10.1016/j.jaac.2025.01.017.Peer-Reviewed Original ResearchIndividual-Participant-DataRepeat self-harmSelf-harmEffective interventionsIPD meta-analysisMeta-analysisCore set of outcome measuresSet of outcome measuresMeta-analysesRepetition of self-harmIntervention to controlIPD meta-analysesMonths post-randomizationMeta-analysis of randomised controlled trialsSelf-harm episodesHistory of self-harmMeta-analysis of RCTsPooled treatment effectsTherapeutic intervention effectivenessSelf-harm incidentsData meta-analysisHeterogeneity of treatment effectsPublic health concernTreatment effectsIntervention effectsPredictions of adolescents’ responses to the Youth Self-Report from parental attachment interviews collected during pregnancy: a 17-year longitudinal study
Perez A, Steele M, Fonagy P, Fearon P, Segal F, Steele H. Predictions of adolescents’ responses to the Youth Self-Report from parental attachment interviews collected during pregnancy: a 17-year longitudinal study. Attachment & Human Development 2025, ahead-of-print: 1-15. PMID: 39817698, DOI: 10.1080/14616734.2024.2448916.Peer-Reviewed Original ResearchAdult Attachment InterviewSelf-reported mental health symptomsMental health symptomsAttachment InterviewFirst-born childrenHealth symptomsParents' Adult Attachment InterviewsParent Attachment InterviewYouth Self-ReportMental health problemsAttachment representationsChild externalizingAttachment patternsInfant-fatherInfant-motherMid-adolescenceMiddle classAdolescents' responsesSelf-reportMothers' responsesUrban sampleAdolescent childrenLongitudinal studyInterviewsChildrenA systemic approach to identifying sustainable community-based interventions for improving adolescent mental health: a participatory group model building and design protocol
Keenan M, Freeman L, Santana de Lima E, Potter K, Hobbs T, Ballard E, Fonagy P. A systemic approach to identifying sustainable community-based interventions for improving adolescent mental health: a participatory group model building and design protocol. Health Research Policy And Systems 2025, 23: 9. PMID: 39806346, PMCID: PMC11727203, DOI: 10.1186/s12961-024-01247-y.Peer-Reviewed Original ResearchConceptsParticipatory group model buildingAdolescent mental healthImprove adolescent mental healthMental healthGroup model buildingMental health of childrenCo-designed interventionsCommunity-based participatoryPerceived mental healthCommunity-based interventionsWell-beingYoung peopleWell-being of young peopleHealth of childrenHealth determinantsSocial determinantsCommunity settingsParticipants' needsCo-designPost-deliveryFidelity evaluationLocal young peopleHealthDesign protocolsCommunity membersAn exploration of the relationship between ineffective modes of mentalization and difficulties related to borderline personality disorder: A network approach
Asztalos L, Senra H, O'Driscoll C, Feigenbaum J, Griem J, King-Casas B, Consortium L, Nolte T, Pratt R, Vaziri F, Montague R, Fonagy P. An exploration of the relationship between ineffective modes of mentalization and difficulties related to borderline personality disorder: A network approach. Journal Of Affective Disorders 2025, 374: 225-234. PMID: 39798709, DOI: 10.1016/j.jad.2025.01.031.Peer-Reviewed Original ResearchConceptsBorderline personality disorderBorderline personality disorder diagnosisPersonality disorderMental modeInterpersonal functioningMixed Graphical ModelsClinical groupsStudy evaluated associationsHypermentalizationMentalHypomentalizationModerating variableSecondary data analysisMental challengesDisordersNetwork analysis approachSignificant linkCross-sectional secondary data analysisIndividualsBorderlineDifficultiesMASCCommunity groupsHypothesisGroup
2024
Help-Seeking and Disclosure in University Students with Suicidal Thoughts and Self-Harm: A Systematic Review
Barnett P, Tickell A, Osborn T, Delamain H, Fonagy P, Pilling S, Gibbon L. Help-Seeking and Disclosure in University Students with Suicidal Thoughts and Self-Harm: A Systematic Review. International Journal Of Mental Health And Addiction 2024, 1-78. DOI: 10.1007/s11469-024-01416-8.Peer-Reviewed Original ResearchHelp-seekingSelf-harmSuicidal thoughtsRates of help-seekingImprove help-seekingSuicide prevention effortsEthnic minority groupsAt-risk groupsPopulation-basedMental healthReview synthesises researchQualitative studyPrevention effortsSystematic reviewPredictive of completed suicideAt-riskUniversity studentsMinority groupsUS-basedSuicidePsycEXTRAPsychINFOHealthMEDLINEInterventionIdentifying subgroups of individuals based on their epistemic stance, attachment dimensions and childhood trauma: A latent profile analysis
Delamain H, Saunders R, Tanzer M, Luyten P, Fonagy P, Campbell C. Identifying subgroups of individuals based on their epistemic stance, attachment dimensions and childhood trauma: A latent profile analysis. Journal Of Psychiatric Research 2024, 181: 701-708. PMID: 39753089, DOI: 10.1016/j.jpsychires.2024.12.033.Peer-Reviewed Original ResearchConceptsLatent profile analysisAttachment dimensionsChildhood traumaSubgroups of individualsMental health symptom severityWellbeing measuresRisk of mental health concernsMental health outcomesMental health concernsMental health symptomsRisk of negative outcomesHealth outcomesFour-profile solutionMental healthHealth symptomsSociodemographic variablesGroup comparison testsEducation levelHigher risk of negative outcomesLinear regression analysisGeneral populationRelationship statusDemographic factorsHealth concernEpistemic stanceMentalizing, epistemic trust and interpersonal problems in emotion regulation: A sequential path analysis across common mental health disorders and community control samples
Kumpasoğlu G, Saunders R, Campbell C, Nolte T, Montague R, Pilling S, Leibowitz J, Fonagy P. Mentalizing, epistemic trust and interpersonal problems in emotion regulation: A sequential path analysis across common mental health disorders and community control samples. Journal Of Affective Disorders 2024, 372: 502-511. PMID: 39694336, DOI: 10.1016/j.jad.2024.12.050.Peer-Reviewed Original ResearchInterpersonal problemsEmotion regulationEmotion dysregulationSequential mediation analysisMental health disordersEpistemic trustMediation analysisCross-sectional design prevents causal inferencesAssociated with emotion dysregulationMultiple mental health disordersHealth disordersCommunity control sampleEffective emotion regulationNon-clinical populationsModerated mediation analysisSample recruitment methodPsychological functioningSocial-communicative aspectsGroup differencesEmotionsMentalPath analysisStudy limitationsSequential path analysisDisordersCultivating participatory processes in self‐harm app development: A case‐study and working methodology
Babbage C, Lockwood J, Roberts L, Mendes J, Greenhalgh C, Willingham L, Wokomah E, Woodcock R, Slovak P, Townsend E, Townsend E, Hollis C, Gregory J, Vallejos E, Woodcock R, Fonagy P, Arseneault L, Doherty S, Willingham L, Creswell C, Lloyd E, De Alcantara Mendes J, Holter C, Jirotka M, Patalay P, Kelly Y, Kandola A, Sonuga‐Barke E, Livingstone S, Kostryka‐Allchorne K, Stoilova M, O'Connor R, Auer D, Lee S, Jawahar N, Etherson M, Greenhalgh C, Sayal K, Warren J, Wanniarachchi V, Stallard P, Hall C, Lucassen M, Merry S, Stasiak K, Babbage C, Parker A, Griffiths H, Roberts L, Slovak P, Williams A, Lockwood J. Cultivating participatory processes in self‐harm app development: A case‐study and working methodology. JCPP Advances 2024, 4: e12295. PMID: 39734924, PMCID: PMC11669782, DOI: 10.1002/jcv2.12295.Peer-Reviewed Original ResearchSelf-harmManagement of self-harmSuicide related behaviorsAdolescent self-harmMental health developmentDigital mental healthMental healthYoung peopleRelated behaviorsPatient involvementFace-to-faceClinical supportHealth developmentCodesign processParticipatory practicesParticipatory aspectsDecision-makingClinical settingClinical toolThe role of epistemic trust and epistemic disruption in vaccine hesitancy, conspiracy thinking and the capacity to identify fake news
Tanzer M, Campbell C, Saunders R, Booker T, Luyten P, Fonagy P. The role of epistemic trust and epistemic disruption in vaccine hesitancy, conspiracy thinking and the capacity to identify fake news. PLOS Global Public Health 2024, 4: e0003941. PMID: 39630644, PMCID: PMC11616851, DOI: 10.1371/journal.pgph.0003941.Peer-Reviewed Original ResearchEpistemic trustField of developmental psychopathologyExposure to childhood adversityFake newsConspiracy thinkingDevelopmental psychopathologyChildhood adversityInterpersonal processesPsychological resilienceSocial functioningConspiracy beliefsEffect sizeEpistemic disruptionPsychopathologyNewsCredulityConspiracy
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