2014
Dynamic peripheral traction forces balance stable neurite tension in regenerating Aplysia bag cell neurons
Hyland C, Mertz AF, Forscher P, Dufresne E. Dynamic peripheral traction forces balance stable neurite tension in regenerating Aplysia bag cell neurons. Scientific Reports 2014, 4: 4961. PMID: 24825441, PMCID: PMC4019958, DOI: 10.1038/srep04961.Peer-Reviewed Original Research
2008
Myosin II Activity Facilitates Microtubule Bundling in the Neuronal Growth Cone Neck
Burnette DT, Ji L, Schaefer AW, Medeiros NA, Danuser G, Forscher P. Myosin II Activity Facilitates Microtubule Bundling in the Neuronal Growth Cone Neck. Developmental Cell 2008, 15: 163-169. PMID: 18606149, PMCID: PMC2548298, DOI: 10.1016/j.devcel.2008.05.016.Peer-Reviewed Original ResearchCoordination of Actin Filament and Microtubule Dynamics during Neurite Outgrowth
Schaefer AW, Schoonderwoert VT, Ji L, Mederios N, Danuser G, Forscher P. Coordination of Actin Filament and Microtubule Dynamics during Neurite Outgrowth. Developmental Cell 2008, 15: 146-162. PMID: 18606148, PMCID: PMC2595147, DOI: 10.1016/j.devcel.2008.05.003.Peer-Reviewed Original ResearchConceptsRetrograde actin network flowActin network flowNeurite outgrowthMyosin II contractilityRho-kinaseCell adhesion substratesCytoskeletal dynamicsMicrotubule behaviorAdhesion sitesAdhesion substrateMicrotubule dynamicsMyosin IIActin filamentsMolecular eventsGrowth responseMicrotubule movementKinaseNeuronal growthMicrotubulesOutgrowthGrowth cone neckGrowthOrganellesRegulationCascade
2007
Filopodial actin bundles are not necessary for microtubule advance into the peripheral domain of Aplysia neuronal growth cones
Burnette DT, Schaefer AW, Ji L, Danuser G, Forscher P. Filopodial actin bundles are not necessary for microtubule advance into the peripheral domain of Aplysia neuronal growth cones. Nature Cell Biology 2007, 9: 1360-1369. PMID: 18026092, DOI: 10.1038/ncb1655.Peer-Reviewed Original Research
2001
Protein Kinase C Activation Promotes Microtubule Advance in Neuronal Growth Cones by Increasing Average Microtubule Growth Lifetimes
Kabir N, Schaefer A, Nakhost A, Sossin W, Forscher P. Protein Kinase C Activation Promotes Microtubule Advance in Neuronal Growth Cones by Increasing Average Microtubule Growth Lifetimes. Journal Of Cell Biology 2001, 152: 1033-1044. PMID: 11238458, PMCID: PMC2198821, DOI: 10.1083/jcb.152.5.1033.Peer-Reviewed Original Research
1998
The Ig Superfamily Cell Adhesion Molecule, apCAM, Mediates Growth Cone Steering by Substrate–Cytoskeletal Coupling
Suter D, Errante L, Belotserkovsky V, Forscher P. The Ig Superfamily Cell Adhesion Molecule, apCAM, Mediates Growth Cone Steering by Substrate–Cytoskeletal Coupling. Journal Of Cell Biology 1998, 141: 227-240. PMID: 9531561, PMCID: PMC2132711, DOI: 10.1083/jcb.141.1.227.Peer-Reviewed Original ResearchMeSH KeywordsActinsAnimalsAplysiaCell Adhesion MoleculesCell MovementCells, CulturedCloning, MolecularCytoskeletonDNA PrimersGanglia, InvertebrateImmunoglobulin GKineticsMicroscopy, VideoMicrotubulesModels, BiologicalNeuronsPolymerase Chain ReactionRecombinant ProteinsSilicon DioxideStress, MechanicalTubulin
1995
Growth cone advance is inversely proportional to retrograde F-actin flow
Lin C, Forscher P. Growth cone advance is inversely proportional to retrograde F-actin flow. Neuron 1995, 14: 763-771. PMID: 7536426, DOI: 10.1016/0896-6273(95)90220-1.Peer-Reviewed Original Research
1994
Cytoskeletal reorganization underlying growth cone motility
Lin C, Thompson C, Forscher P. Cytoskeletal reorganization underlying growth cone motility. Current Opinion In Neurobiology 1994, 4: 640-647. PMID: 7849519, DOI: 10.1016/0959-4388(94)90004-3.Peer-Reviewed Original ResearchConceptsIndividual cytoskeletal elementsGrowth cone motilityCytoskeletal dynamicsCytoskeletal reorganizationIntracellular cytoskeletonExtracellular substratesCytoskeletal elementsLiving cellsCone motilityNeuronal migrationNeuronal outgrowthFunctional couplingRecent studiesCytoskeletonImportant componentRegulation