2019
Development of an Antibiotic Guideline for Children With Suspected Ventilator-Associated Infections.
Shein SL, Karam O, Beardsley A, Karsies T, Prentice E, Tarquinio KM, Willson DF. Development of an Antibiotic Guideline for Children With Suspected Ventilator-Associated Infections. Pediatric Critical Care Medicine 2019, 20: 697-706. PMID: 30985606, DOI: 10.1097/pcc.0000000000001942.Peer-Reviewed Original ResearchConceptsVentilator-associated infectionPhase 1 dataAntibiotic guidelinesGuideline scoreAntibiotic usePediatric Logistic Organ Dysfunction-2 scoreDuration of antibioticsPICU-free daysVentilator-Associated InfectionsVentilator-free daysInitiation of antibioticsProspective data collectionPhase 3Median ageMechanical ventilationVentilated childrenScore 3Consensus conferenceClinical testingScoring systemInfectionLiterature searchExpert panelAntibioticsScores
2013
Optimizing Patient-Ventilator Synchrony During Invasive Ventilator Assist in Children and Infants Remains a Difficult Task*
Vignaux L, Grazioli S, Piquilloud L, Bochaton N, Karam O, Jaecklin T, Levy-Jamet Y, Tourneux P, Jolliet P, Rimensberger PC. Optimizing Patient-Ventilator Synchrony During Invasive Ventilator Assist in Children and Infants Remains a Difficult Task*. Pediatric Critical Care Medicine 2013, 14: e316-e325. PMID: 23842584, DOI: 10.1097/pcc.0b013e31828a8606.Peer-Reviewed Original ResearchConceptsAsynchrony eventsVentilatory assistExpiratory triggerInspiratory timeAsynchrony indexNeonatal intensive care unitIntensive care unitPressure support modePatient-ventilator synchronyPressure supportMedian asynchrony indexCare unitCrossover studyMechanical ventilationVentilated childrenVentilator assistUniversity HospitalPremature cyclingClinical impactRandom orderVentilation periodIneffective effortsFurther studiesChildrenSupport mode