2022
Anticoagulation strategies and recurrence of venous thromboembolic events in patients with sickle cell disease: a systematic review and meta-analysis
El-Amin N, Iness A, Cyrus JW, Sisler I, Karam O. Anticoagulation strategies and recurrence of venous thromboembolic events in patients with sickle cell disease: a systematic review and meta-analysis. Annals Of Hematology 2022, 101: 1931-1940. PMID: 35895101, DOI: 10.1007/s00277-022-04901-z.Peer-Reviewed Original ResearchConceptsVenous thromboembolic eventsSickle cell diseaseCell diseaseThromboembolic eventsPulmonary embolismSystematic reviewDevelopment of bleedingOverall bleeding rateVenous thrombotic eventsRisk of mortalityProgression of thrombusAnticoagulant classDifferent anticoagulationAnticoagulation strategiesOverall recurrenceOverall mortalityThrombotic eventsAdverse outcomesPatient populationBleeding rateObservational studyOutcome measuresAppropriate managementPatientsRecurrence
2016
The effect of inhaled nitric oxide in acute respiratory distress syndrome in children and adults: a Cochrane Systematic Review with trial sequential analysis
Karam O, Gebistorf F, Wetterslev J, Afshari A. The effect of inhaled nitric oxide in acute respiratory distress syndrome in children and adults: a Cochrane Systematic Review with trial sequential analysis. Anaesthesia 2016, 72: 106-117. PMID: 27762438, DOI: 10.1111/anae.13628.Peer-Reviewed Original Research
2013
Association between plasma transfusions and clinical outcome in critically ill children: a prospective observational study
Karam O, Lacroix J, Robitaille N, Rimensberger PC, Tucci M. Association between plasma transfusions and clinical outcome in critically ill children: a prospective observational study. Vox Sanguinis 2013, 104: 342-349. PMID: 23294337, DOI: 10.1111/vox.12009.Peer-Reviewed Original ResearchConceptsProgressive multiple organ dysfunction syndromeMultiple organ dysfunction syndromeOrgan dysfunction syndromeIntensive care unit lengthPlasma transfusionDysfunction syndromeClinical outcomesIll childrenNosocomial infectionsCare unitOdds ratioOutcome measuresPediatric intensive care unitPediatric critical care unitProspective pediatric studiesAdult trauma patientsProspective observational studySingle-center studySecondary outcome measuresWorse clinical outcomesExtracorporeal life supportPrimary outcome measureSeverity of illnessIntensive care unitCritical care units