2018
Platelet Transfusion Practices in Critically Ill Children
Nellis ME, Karam O, Mauer E, Cushing MM, Davis PJ, Steiner ME, Tucci M, Stanworth SJ, Spinella PC. Platelet Transfusion Practices in Critically Ill Children. Critical Care Medicine 2018, 46: 1309-1317. PMID: 29727368, PMCID: PMC6476545, DOI: 10.1097/ccm.0000000000003192.Peer-Reviewed Original ResearchConceptsPlatelet transfusionsCells/LMajor bleedingProphylactic transfusionICU mortalityMinor bleedingIll childrenOverall ICU mortalityPediatric critical illnessPlatelet transfusion practicesProspective cohort studyProphylactic platelet transfusionsCohort studyCritical illnessPost transfusionAdjusted analysisPlatelet countTransfusion practiceAppropriate indicationsMedian changePlatelet doseTransfusionBleedingCells/L.Prophylaxis
2015
Indications and Effects of Plasma Transfusions in Critically Ill Children
Karam O, Demaret P, Shefler A, Leteurtre S, Spinella PC, Stanworth SJ, Tucci M. Indications and Effects of Plasma Transfusions in Critically Ill Children. American Journal Of Respiratory And Critical Care Medicine 2015, 191: 1395-1402. PMID: 25859890, DOI: 10.1164/rccm.201503-0450oc.Peer-Reviewed Original ResearchConceptsInternational normalized ratioMedian international normalized ratioPlasma transfusionIll childrenCoagulation testsBaseline international normalized ratioPediatric intensive care patientsPediatric intensive care unitPartial thromboplastin time valuesCritically Ill ChildrenPoint prevalence studyIntensive care patientsIntensive care unitStrong evidence baseMinor bleedingPostoperative bleedingMost patientsPatient characteristicsTransfusion strategyCare patientsCare unitCritical bleedingNormalized ratioPrimary indicationTransfusion
2013
International survey on plasma transfusion practices in critically ill children
Karam O, Tucci M, Lacroix J, Rimensberger PC, Network C. International survey on plasma transfusion practices in critically ill children. Transfusion 2013, 54: 1125-1132. PMID: 24032693, DOI: 10.1111/trf.12393.Peer-Reviewed Original ResearchConceptsTraumatic brain injuryPediatric critical care physiciansPlasma transfusion practicesInternational normalized ratioCritical care physiciansPlasma transfusionTransfusion practiceCare physiciansRed blood cell transfusion practicesAbnormal international normalized ratioPediatric critical care unitCardiac postoperative patientsTransfusion practice patternsSeptic shock patientsDemographic characteristicsCritical care unitsPartial thromboplastin timeProportion of physiciansFallot correctionNonbleeding patientsMinor bleedingShock patientsTransfusion thresholdPostoperative patientsSeptic shock