2018
Effects of plasma transfusions on antithrombin levels after paediatric liver transplantation
Arni D, Wildhaber BE, McLin V, Rimensberger PC, Ansari M, Fontana P, Karam O. Effects of plasma transfusions on antithrombin levels after paediatric liver transplantation. Vox Sanguinis 2018, 113: 569-576. PMID: 29761839, DOI: 10.1111/vox.12664.Peer-Reviewed Original ResearchLiver transplantationPediatric liver transplantationPlasma transfusionAT levelsProspective single-center observational studySingle-center observational studyPediatric LT patientsProphylactic plasma transfusionPro-thrombotic profileLife-threatening complicationsPediatric LT recipientsOptimal anticoagulation strategyPro-coagulant factorsNon-inferiority hypothesisLT patientsAnticoagulation strategiesLT recipientsAntithrombin levelsThrombotic complicationsMedian agePatient weightObservational studyRoutine managementTransfusionBlood samples
2017
Rapid detection and ruling out of neonatal sepsis by PCR coupled with Electrospray Ionization Mass Spectrometry (PCR/ESI-MS)
Delcò C, Karam O, Pfister R, Gervaix A, Renzi G, Emonet S, Schrenzel J, Posfay-Barbe KM. Rapid detection and ruling out of neonatal sepsis by PCR coupled with Electrospray Ionization Mass Spectrometry (PCR/ESI-MS). Early Human Development 2017, 108: 17-22. PMID: 28343091, DOI: 10.1016/j.earlhumdev.2017.03.004.Peer-Reviewed Original ResearchConceptsNegative predictive valuePCR/ESI-MSBlood culturesPredictive valueNeonatal sepsisGood negative predictive valueProspective observational studyBlood culture resultsInitiation of antibioticsPositive blood culturesConventional blood culturePositive predictive valueEmpiric antibioticsConsecutive neonatesAdverse eventsClinical suspicionMedian ageNeonatal populationObservational studySepsisBlood samplesEarly reassessmentImportant causeCulture resultsBacterial infections