2020
Epidemiology of Hemostatic Transfusions in Children Supported by Extracorporeal Membrane Oxygenation.
Karam O, Goel R, Dalton H, Nellis ME. Epidemiology of Hemostatic Transfusions in Children Supported by Extracorporeal Membrane Oxygenation. Critical Care Medicine 2020, 48: e698-e705. PMID: 32697511, DOI: 10.1097/ccm.0000000000004417.Peer-Reviewed Original ResearchConceptsExtracorporeal membrane oxygenationCollaborative Pediatric Critical Care Research NetworkChest tube outputMembrane oxygenationHemostatic transfusionsRBC transfusionTransfusion doseExtracorporeal membrane oxygenation daysLarge observational cohort studyEunice Kennedy Shriver National InstituteCritical Care Research NetworkTube outputPlatelet transfusion doseObservational cohort studyHuman Development Collaborative Pediatric Critical Care Research NetworkInternational normalized ratioTotal platelet countPartial thromboplastin timeAntithrombin levelsCohort studyConsecutive childrenTransfusion strategyChest tubePlatelet countHemostatic testing
2018
Effects of plasma transfusions on antithrombin levels after paediatric liver transplantation
Arni D, Wildhaber BE, McLin V, Rimensberger PC, Ansari M, Fontana P, Karam O. Effects of plasma transfusions on antithrombin levels after paediatric liver transplantation. Vox Sanguinis 2018, 113: 569-576. PMID: 29761839, DOI: 10.1111/vox.12664.Peer-Reviewed Original ResearchLiver transplantationPediatric liver transplantationPlasma transfusionAT levelsProspective single-center observational studySingle-center observational studyPediatric LT patientsProphylactic plasma transfusionPro-thrombotic profileLife-threatening complicationsPediatric LT recipientsOptimal anticoagulation strategyPro-coagulant factorsNon-inferiority hypothesisLT patientsAnticoagulation strategiesLT recipientsAntithrombin levelsThrombotic complicationsMedian agePatient weightObservational studyRoutine managementTransfusionBlood samples