1990
Neonatal Excitotoxic Brain Injury
Young R, Petroff O, Novotny E, Wong M. Neonatal Excitotoxic Brain Injury. Developmental Neuroscience 1990, 12: 210-220. PMID: 2142073, DOI: 10.1159/000111850.Peer-Reviewed Original ResearchConceptsQuisqualic acidBrain injuryNeonatal excitotoxic brain injuryExcitotoxic brain injuryHypoxic-ischemic injuryNeonatal rat brainN-acetyl aspartateExcitotoxic damageNeuronal necrosisNeuropathologic examinationParoxysmal dischargesNeonatal ratsElectroencephalographic monitoringHilar areaRat brainMedial CA1Pathologic alterationsMetabolic alterationsParahippocampal regionPathological effectsGlutamate analogueInjuryPhysiologicUnique patternAlterations
1989
Thromboxane synthesis inhibitor in a beagle pup model of perinatal asphyxia.
Ment L, Stewart W, Petroff O, Duncan C. Thromboxane synthesis inhibitor in a beagle pup model of perinatal asphyxia. Stroke 1989, 20: 809-814. PMID: 2728050, DOI: 10.1161/01.str.20.6.809.Peer-Reviewed Original ResearchConceptsCerebral blood flowThromboxane synthesis inhibitorBlood flowPerinatal asphyxiaSynthesis inhibitorCGS 13080Intraventricular hemorrhageLactate levelsCerebral regionsHigh incidenceMetabolic alterationsWhite matterLactate concentrationAsphyxiaBrain extractsInsultPhosphocreatine concentrationPupsSalineInhibitorsHemorrhageProstaglandinsMedulla