2012
Regulation of prefrontal excitatory neurotransmission by dopamine in the nucleus accumbens core
Wang W, Dever D, Lowe J, Storey GP, Bhansali A, Eck EK, Nitulescu I, Weimer J, Bamford NS. Regulation of prefrontal excitatory neurotransmission by dopamine in the nucleus accumbens core. The Journal Of Physiology 2012, 590: 3743-3769. PMID: 22586226, PMCID: PMC3476631, DOI: 10.1113/jphysiol.2012.235200.Peer-Reviewed Original ResearchMeSH KeywordsAdenosineAmphetamineAnimalsDopamineEndocannabinoidsGreen Fluorescent ProteinsMaleMiceMice, TransgenicNucleus AccumbensOptical ImagingPrefrontal CortexPresynaptic TerminalsPyridinium CompoundsQuaternary Ammonium CompoundsReceptors, AMPAReceptors, Dopamine D1Receptors, GlutamateReceptors, N-Methyl-D-AspartateSynaptic TransmissionConceptsD2 receptor-expressing cellsReceptor-expressing cellsMedium spiny neuronsSpiny neuronsExcitatory inputsD2 receptor-expressing medium spiny neuronsReceptor-expressing medium spiny neuronsGroup 1 metabotropic glutamate receptorsActivation of NMDAReceptor null miceMetabotropic glutamate receptorsBacterial artificial chromosome transgenic miceDopamine D1 receptorsBasal ganglia pathwaysConvergence of excitatoryNucleus accumbens coreCortical terminalsGlutamate releaseGlutamatergic inputsStriatonigral pathwayInhibitory modulationGlutamatergic signalsD1 receptorsSlice preparationGlutamatergic synapses
2006
362 ROLE OF ACETYLCHOLINE IN PSYCHOSTIMULANT ADDICTION.
Kumar T, Joyce J, Bamford N. 362 ROLE OF ACETYLCHOLINE IN PSYCHOSTIMULANT ADDICTION. Journal Of Investigative Medicine 2006, 54: s142. DOI: 10.2310/6650.2005.x0004.361.Peer-Reviewed Original ResearchMedium spiny neuronsWithdrawal day 1Nucleus accumbensCholinergic activationCholinergic interneuronsBasal gangliaSpiny neuronsDorsolateral striatumDay 1Striatal medium spiny neuronsAdult C57B1/6 miceCaudal nucleus accumbensChronic METH treatmentExcitatory glutamatergic projectionsWithdrawal day 10Striatal cholinergic interneuronsC-fosTreatment of miceC-Fos immunoreactivityRole of acetylcholineNumber of ChATImmediate early gene expressionChronic METHCortical terminalsGlutamate release