2023
Association of rs9939609 in FTO with BMI among Polynesian peoples living in Aotearoa New Zealand and other Pacific nations
Krishnan M, Phipps-Green A, Russell E, Major T, Cadzow M, Stamp L, Dalbeth N, Hindmarsh J, Qasim M, Watson H, Liu S, Carlson J, Minster R, Hawley N, Naseri T, Reupena M, Deka R, McGarvey S, Merriman T, Murphy R, Weeks D. Association of rs9939609 in FTO with BMI among Polynesian peoples living in Aotearoa New Zealand and other Pacific nations. Journal Of Human Genetics 2023, 68: 463-468. PMID: 36864286, PMCID: PMC10313811, DOI: 10.1038/s10038-023-01141-5.Peer-Reviewed Original ResearchConceptsBody mass indexMean body mass indexHigher body mass indexPrevious smaller studiesAssociation of rs9939609New Zealand PolynesiansMass indexFat massSmall studySignificant associationPolynesian ancestryFTO variantsRs9939609Effect size estimatesAssociationSimilar effectsMean effect size estimate
2022
Multivariate analysis of a missense variant in CREBRF reveals associations with measures of adiposity in people of Polynesian ancestries
Zhang J, Heinsberg L, Krishnan M, Hawley N, Major T, Carlson J, Hindmarsh J, Watson H, Qasim M, Stamp L, Dalbeth N, Murphy R, Sun G, Cheng H, Naseri T, Reupena M, Kershaw E, Deka R, McGarvey S, Minster R, Merriman T, Weeks D. Multivariate analysis of a missense variant in CREBRF reveals associations with measures of adiposity in people of Polynesian ancestries. Genetic Epidemiology 2022, 47: 105-118. PMID: 36352773, PMCID: PMC9892232, DOI: 10.1002/gepi.22508.Peer-Reviewed Original ResearchCREBRF missense variant rs373863828 has both direct and indirect effects on type 2 diabetes and fasting glucose in Polynesian peoples living in Samoa and Aotearoa New Zealand
Russell EM, Carlson JC, Krishnan M, Hawley NL, Sun G, Cheng H, Naseri T, Reupena M, Viali S, Tuitele J, Major TJ, Miljkovic I, Merriman TR, Deka R, Weeks DE, McGarvey ST, Minster RL. CREBRF missense variant rs373863828 has both direct and indirect effects on type 2 diabetes and fasting glucose in Polynesian peoples living in Samoa and Aotearoa New Zealand. BMJ Open Diabetes Research & Care 2022, 10: e002275. PMID: 35144939, PMCID: PMC8845200, DOI: 10.1136/bmjdrc-2021-002275.Peer-Reviewed Original ResearchConceptsBody mass indexType 2 diabetesAssociation of BMIHigher body mass indexMinor alleleType 2 diabetes riskCross-sectional associationsPacific Island populationsRs373863828 genotypeMass indexDiabetes riskHigher oddsLower oddsDiabetesObesityEvidence of differencesMissense variantsRs373863828Regression analysisGlucoseAssociationOddsIndirect effectsPolynesian individuals
2020
Longitudinal Assessment of Childhood Dietary Patterns: Associations with Body Mass Index z-Score among Children in the Samoan Ola Tuputupua'e (Growing Up) Cohort
Choy CC, Wang D, Naseri T, Soti-Ulberg C, Reupena MS, Duckham RL, Baylin A, Hawley NL. Longitudinal Assessment of Childhood Dietary Patterns: Associations with Body Mass Index z-Score among Children in the Samoan Ola Tuputupua'e (Growing Up) Cohort. Childhood Obesity 2020, 16: 534-543. PMID: 32907355, PMCID: PMC7575349, DOI: 10.1089/chi.2020.0058.Peer-Reviewed Original ResearchConceptsDietary patternsHigh adherenceBody mass index zChildhood obesity prevention strategiesObesity prevention strategiesBody mass indexFood frequency dataChildhood dietary patternsBiological mother-child dyadsCohort studyMass indexPattern adherencePotential confoundersChildhood obesityPrevention strategiesMother-child dyadsLongitudinal assessmentTime pointsConvenience sampleAdherenceBMIzIntervention strategiesChildrenScoresAssociationEstimated Dietary Bisphenol-A Exposure and Adiposity in Samoan Mothers and Children
Heinsberg LW, Bui CNN, Hartle JC, Sereika SM, Choy CC, Wang D, Soti-Ulberg C, Naseri T, Reupena MS, Duckham RL, Park JJ, Hawley NL, Deziel NC. Estimated Dietary Bisphenol-A Exposure and Adiposity in Samoan Mothers and Children. Toxics 2020, 8: 67. PMID: 32887300, PMCID: PMC7560430, DOI: 10.3390/toxics8030067.Peer-Reviewed Original ResearchBody mass indexDietary BPA exposureAbdominal circumferenceBPA exposureModern dietary patternBisphenol A (BPA) exposureMother-child pairsDietary questionnaireMass indexPrevalent obesityFoods/beveragesDietary patternsSamoan mothersSignificant associationEndocrine disruptor bisphenolHigher incomeUnderstudied populationExposure indexMothersChildrenExposureFurther examinationAssociationHousehold-level characteristicsIndex