2013
An LC–MS assay for the screening of cardiovascular medications in human samples
Dias E, Hachey B, McNaughton C, Nian H, Yu C, Straka B, Brown NJ, Caprioli RM. An LC–MS assay for the screening of cardiovascular medications in human samples. Journal Of Chromatography B 2013, 937: 44-53. PMID: 24013190, PMCID: PMC3800555, DOI: 10.1016/j.jchromb.2013.08.010.Peer-Reviewed Original ResearchMeSH KeywordsCardiovascular AgentsChromatography, LiquidDrug MonitoringHumansLimit of DetectionLinear ModelsReproducibility of ResultsTandem Mass SpectrometryConceptsAngiotensin II receptor blockersDrug metabolitesCardiovascular drugsDrug classesHospitalized patientsSingle LC-MS/MS methodLC-MS assayLC-MS/MS methodII receptor blockersCalcium channel blockersCardiovascular drug classesClinical samplesDrug detectionSpiked samplesMS methodCardiovascular medicationsReceptor blockersBeta blockersMedication administrationChannel blockersEnzyme inhibitorsClinical settingBlockersDrugsSimultaneous analysis
2008
Simultaneous determination of uric acid metabolites allantoin, 6-aminouracil, and triuret in human urine using liquid chromatography–mass spectrometry
Kim KM, Henderson GN, Frye RF, Galloway CD, Brown NJ, Segal MS, Imaram W, Angerhofer A, Johnson RJ. Simultaneous determination of uric acid metabolites allantoin, 6-aminouracil, and triuret in human urine using liquid chromatography–mass spectrometry. Journal Of Chromatography B 2008, 877: 65-70. PMID: 19081307, PMCID: PMC2684329, DOI: 10.1016/j.jchromb.2008.11.029.Peer-Reviewed Original ResearchMeSH KeywordsAllantoinCalibrationChromatography, High Pressure LiquidHumansReference StandardsReproducibility of ResultsSpectrometry, Mass, Electrospray IonizationUracilUreaConceptsUric acidUrinary metabolitesOxidative stressSelected-reaction monitoringUrinary creatinineNormal individualsNitric oxideUrine samplesLiquid chromatography-mass spectrometryBiological samplesPositive ion modeTandem mass spectrometry methodHigh-performance liquid chromatographyMass spectrometry methodChromatography-mass spectrometryUrineInter-day precisionMetabolitesUrinary allantoinIon modeLC-MS/MS analysisHuman urineGradient HPLCMost mammalsSpectrometry method
1994
Simplified assay for the quantification of 2,3-dinor-6-ketoprostaglandin F1α by gas chromatography—mass spectrometry
Daniel V, Minton T, Brown N, Nadeau J, Morrow J. Simplified assay for the quantification of 2,3-dinor-6-ketoprostaglandin F1α by gas chromatography—mass spectrometry. Journal Of Chromatography B 1994, 653: 117-122. PMID: 8205238, DOI: 10.1016/0378-4347(93)e0432-p.Peer-Reviewed Original ResearchMeSH Keywords6-Ketoprostaglandin F1 alphaEpoprostenolGas Chromatography-Mass SpectrometryHumansReference ValuesReproducibility of Results