2024
Stimulation Therapy to Induce Mothers: Protocol for a Multicenter Randomized Controlled Trial
Tortal D, Shabanova V, Taylor S, Xu X, McAdow M, Stetson B, McCollum S, Sanchez E, Adjakple A, Leventhal J, Son M. Stimulation Therapy to Induce Mothers: Protocol for a Multicenter Randomized Controlled Trial. JMIR Research Protocols 2024, 13: e63463. PMID: 39207839, PMCID: PMC11393510, DOI: 10.2196/63463.Peer-Reviewed Original ResearchDyadic care to improve postnatal outcomes of birthing people and their infants: A scoping review protocol
Choy C, McAdow M, Rosenberg J, Grimshaw A, Martinez-Brockman J. Dyadic care to improve postnatal outcomes of birthing people and their infants: A scoping review protocol. PLOS ONE 2024, 19: e0298927. PMID: 38625992, PMCID: PMC11020692, DOI: 10.1371/journal.pone.0298927.Peer-Reviewed Original ResearchConceptsCare interventionsBirthing personsHealth outcomesCare studiesJoanna Briggs Institute critical appraisal toolsPostnatal health outcomesReduce healthcare disparitiesImprove healthcare deliveryProvision of careCritical appraisal toolsWHO regional databasesRisk of biasOpen Science FrameworkObstetric careHealthcare disparitiesImplementation outcomesNarrative synthesisAppraisal ToolImprove disparitiesHealthcare deliveryGrey literaturePractice gapReview protocolWeb of Science Core CollectionHealthcare systemNipple stimulation therapy promotes uterine contractions at lower plasma oxytocin concentration than intravenous oxytocin during labor induction
McAdow M, Tortal D, Shabanova V, Son M. Nipple stimulation therapy promotes uterine contractions at lower plasma oxytocin concentration than intravenous oxytocin during labor induction. American Journal Of Obstetrics & Gynecology MFM 2024, 6: 101307. PMID: 38331190, DOI: 10.1016/j.ajogmf.2024.101307.Peer-Reviewed Original Research
2022
Normal Laboratory Values in Pregnancy
Lockwood, Charles J., et al. Creasy & Resnik’s Maternal-fetal Medicine: Principles and Practice. 9th edition. Amsterdam: Elsevier.ChaptersMyometrial‐derived CXCL12 promotes lipopolysaccharide induced preterm labour by regulating macrophage migration, polarization and function in mice
Zhang L, Mamillapalli R, Habata S, McAdow M, Taylor HS. Myometrial‐derived CXCL12 promotes lipopolysaccharide induced preterm labour by regulating macrophage migration, polarization and function in mice. Journal Of Cellular And Molecular Medicine 2022, 26: 2566-2578. PMID: 35318804, PMCID: PMC9077289, DOI: 10.1111/jcmm.17252.Peer-Reviewed Original ResearchConceptsInflammation-related cytokinesSmooth muscle cellsPreterm laborCXCL12/CXCR4Preterm birthMacrophage migrationIL-6M1 polarizationPregnant miceImmune cellsCXCL12/CXCR4 axisTreatment of SMCsTumor necrosis factor alphaInduced preterm laborInfiltration of neutrophilsMacrophage M1 polarizationStart of labourNecrosis factor alphaTNF-α expressionPrimary smooth muscle cellsPremature laborPregnancy durationGestational tissuesMacrophage infiltrationNeonatal mortality
2020
Association of Oxytocin Rest During Labor Induction of Nulliparous Women With Mode of Delivery.
McAdow M, Xu X, Lipkind H, Reddy UM, Illuzzi JL. Association of Oxytocin Rest During Labor Induction of Nulliparous Women With Mode of Delivery. Obstetrics And Gynecology 2020, 135: 569-575. PMID: 32028487, DOI: 10.1097/aog.0000000000003709.Peer-Reviewed Original ResearchConceptsMode of deliveryInduction of laborNeonatal morbidityCesarean deliveryNulliparous womenLatent laborOxytocin infusionLatent phaseMultivariable logistic regression analysisContinuous oxytocin infusionRetrospective cohort analysisLarge academic medical centerBody mass indexLogistic regression analysisAcademic medical centerContinuous oxytocinSingleton gestationsLabor inductionGestational ageMass indexPotential confoundersMaternal ageOdds ratioCohort analysisMedical Center
2017
Isolated port site recurrence of node-negative clinical stage IB1 cervical adenocarcinoma
Deshmukh U, McAdow M, Black J, Hui P, Azodi M. Isolated port site recurrence of node-negative clinical stage IB1 cervical adenocarcinoma. Gynecologic Oncology Reports 2017, 20: 54-57. PMID: 28331901, PMCID: PMC5348602, DOI: 10.1016/j.gore.2017.03.001.Peer-Reviewed Case Reports and Technical NotesStage IB1 cervical adenocarcinomaPort site recurrenceLymph nodesCervical adenocarcinomaLaparoscopic surgeryMetastatic diseaseCase reportSite recurrenceAssistant portEarly-stage cervical adenocarcinomaPelvic lymph node dissectionRobotic-assisted laparoscopic surgeryRobotic-assisted radical hysterectomyLymph node dissectionNegative lymph nodesNegative surgical marginsPort-site metastasisYear old womanFirst case reportSoft tissue massInvasive endocervical adenocarcinomaBilateral salpingectomyNode dissectionRadical hysterectomyFinal pathology
2016
Connect the Dots—September 2016
Saunders KT, Washington KL, McAdow M, Chescheir NC. Connect the Dots—September 2016. Obstetrics And Gynecology 2016, 128: 653-654. PMID: 27500325, DOI: 10.1097/aog.0000000000001602.Commentaries, Editorials and LettersAntibodies against a secreted product of Staphylococcus aureus trigger phagocytic killing
Thomer L, Emolo C, Thammavongsa V, Kim H, McAdow M, Yu W, Kieffer M, Schneewind O, Missiakas D. Antibodies against a secreted product of Staphylococcus aureus trigger phagocytic killing. Journal Of Experimental Medicine 2016, 213: 293-301. PMID: 26880578, PMCID: PMC4813671, DOI: 10.1084/jem.20150074.Peer-Reviewed Original ResearchConceptsMethicillin-resistant Staphylococcus aureusBloodstream infectionsPhagocytic killingElicit cross-protective immune responsesCross-protective immune responsesProtective fibrin shieldS. aureus vaccineAureus vaccineClinical efficacyMRSA isolatesImmune cellsOpsonophagocytic killingFrequent causeImmune responseHost immunityHost prothrombinProtective antigenSpecific antibodiesInfectionSurface moleculesAntibodiesS. aureusStaphylococcus aureusAntibody therapeuticsStaphylococcal surface
2012
Coagulases as Determinants of Protective Immune Responses against Staphylococcus aureus
McAdow M, DeDent AC, Emolo C, Cheng AG, Kreiswirth BN, Missiakas DM, Schneewind O. Coagulases as Determinants of Protective Immune Responses against Staphylococcus aureus. Infection And Immunity 2012, 80: 3389-3398. PMID: 22825443, PMCID: PMC3457572, DOI: 10.1128/iai.00562-12.Peer-Reviewed Original ResearchStaphylococcus aureus Secretes Coagulase and von Willebrand Factor Binding Protein to Modify the Coagulation Cascade and Establish Host Infections
McAdow M, Missiakas DM, Schneewind O. Staphylococcus aureus Secretes Coagulase and von Willebrand Factor Binding Protein to Modify the Coagulation Cascade and Establish Host Infections. Journal Of Innate Immunity 2012, 4: 141-148. PMID: 22222316, PMCID: PMC3388267, DOI: 10.1159/000333447.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsFormation of abscessesDrug-resistant S. aureusHost immune cellsHospital-acquired infectionsFactor binding proteinInnate defense mechanismsVon Willebrand factorThromboembolic lesionsClotting of plasmaPreclinical evidenceLethal sepsisImmune cellsStaphylococcal infectionsDisease pathogenesisCoagulation productsClinical isolatesCurrent epidemicKey innate defence mechanismCoagulation cascadeStaphylococcal productsInfectionWillebrand factorOpsonophagocytic clearanceHost infectionFibrin meshwork
2011
Preventing Staphylococcus aureus Sepsis through the Inhibition of Its Agglutination in Blood
McAdow M, Kim HK, DeDent AC, Hendrickx AP, Schneewind O, Missiakas DM. Preventing Staphylococcus aureus Sepsis through the Inhibition of Its Agglutination in Blood. PLOS Pathogens 2011, 7: e1002307. PMID: 22028651, PMCID: PMC3197598, DOI: 10.1371/journal.ppat.1002307.Peer-Reviewed Original ResearchMeSH KeywordsAgglutinationAnimalsAntibodies, NeutralizingAntithrombinsBacterial ProteinsCarrier ProteinsCoagulantsCoagulaseDisease Models, AnimalHeartHost-Pathogen InteractionsHumansImmunization, PassiveLongevityMiceMice, Inbred BALB CMyocardiumProtein BindingSepsisStaphylococcal InfectionsStaphylococcus aureusVon Willebrand FactorConceptsAureus sepsisLethal outcomeDabigatran etexilate treatmentS. aureus sepsisDirect thrombin inhibitorStaphylococcus aureus sepsisStaphylococcus aureus infectionVon Willebrand factorThromboembolic lesionsStaphylococcal sepsisAureus infectionFrequent causeMouse modelSepsisDisease pathogenesisHigh mortalityThrombin inhibitorsBacterial factorsSpecific interventionsHeart tissueWillebrand factorFibrin cableVirulence genesAgglutinationDisease
2010
Contribution of Coagulases towards Staphylococcus aureus Disease and Protective Immunity
Cheng AG, McAdow M, Kim HK, Bae T, Missiakas DM, Schneewind O. Contribution of Coagulases towards Staphylococcus aureus Disease and Protective Immunity. PLOS Pathogens 2010, 6: e1001036. PMID: 20700445, PMCID: PMC2916881, DOI: 10.1371/journal.ppat.1001036.Peer-Reviewed Original ResearchConceptsSpecific antibodiesFormation of abscessesHost immune cellsStaphylococcus aureus diseaseVon Willebrand factorProtective immunityAbscess formationStaphylococcal vaccineImmune cellsLethal bacteremiaNon-proteolytic activationAbscessCleavage of fibrinogenProtective antigenWillebrand factorS. aureusStaphylococcus aureusPseudocapsuleHistochemical stainingAntibodiesProthrombinHost tissuesCoagulaseVWbpAureusIsdA and IsdB antibodies protect mice against Staphylococcus aureus abscess formation and lethal challenge
Kim HK, DeDent A, Cheng AG, McAdow M, Bagnoli F, Missiakas DM, Schneewind O. IsdA and IsdB antibodies protect mice against Staphylococcus aureus abscess formation and lethal challenge. Vaccine 2010, 28: 6382-6392. PMID: 20226248, PMCID: PMC3095377, DOI: 10.1016/j.vaccine.2010.02.097.Peer-Reviewed Original ResearchConceptsIntravenous challengeAbscess formationStaphylococcus aureus abscess formationLethal intravenous challengePathogenesis of infectionHospital-acquired infectionsStaphylococcal abscess formationNaïve miceActive immunizationLethal challengeSurface proteinsOpsonophagocytic killingStaphylococcal diseaseFrequent causeSubunit vaccineExperimental animalsMouse bloodAntibodiesStaphylococcus aureusBind hemoglobinVaccineInfectionMiceStaphylococciBacteremia
2007
Distribution of Protein A on the Surface of Staphylococcus aureus
DeDent AC, McAdow M, Schneewind O. Distribution of Protein A on the Surface of Staphylococcus aureus. Journal Of Bacteriology 2007, 189: 4473-4484. PMID: 17416657, PMCID: PMC1913371, DOI: 10.1128/jb.00227-07.Peer-Reviewed Original Research