2018
GaMRed—Adaptive Filtering of High-Throughput Biological Data
Marczyk M, Jaksik R, Polanski A, Polanska J. GaMRed—Adaptive Filtering of High-Throughput Biological Data. IEEE/ACM Transactions On Computational Biology And Bioinformatics 2018, 17: 149-157. PMID: 30040660, DOI: 10.1109/tcbb.2018.2858825.Peer-Reviewed Original Research
2014
Radiation-induced Changes in Levels of Selected Proteins in Peripheral Blood Serum of Breast Cancer Patients as a Potential Triage Biodosimeter for Large-scale Radiological Emergencies
Deperas-Kaminska M, Bajinskis A, Marczyk M, Polanska J, Wersäll P, Lidbrink E, Ainsbury EA, Guipaud O, Benderitter M, Haghdoost S, Wojcik A. Radiation-induced Changes in Levels of Selected Proteins in Peripheral Blood Serum of Breast Cancer Patients as a Potential Triage Biodosimeter for Large-scale Radiological Emergencies. Health Physics 2014, 107: 555-563. PMID: 25353241, DOI: 10.1097/hp.0000000000000158.Peer-Reviewed Original ResearchConceptsPeripheral blood serumBreast cancer patientsLarge-scale radiological emergencyCancer patientsApolipoprotein EConsistent dose-response relationshipBlood serumExternal beam radiotherapyIrradiation of skinKinase 4Dose-response relationshipLogistic regression modelsPartial-body exposuresPurpose of triageMultinomial logistic regression modelsBeam radiotherapyBlood samplesFetuin BMultivariate analysisBody exposureDifferent dosesRadiation-induced changesSerumProtein 7Factor X
2013
Adaptive filtering of microarray gene expression data based on Gaussian mixture decomposition
Marczyk M, Jaksik R, Polanski A, Polanska J. Adaptive filtering of microarray gene expression data based on Gaussian mixture decomposition. BMC Bioinformatics 2013, 14: 101. PMID: 23510016, PMCID: PMC3637832, DOI: 10.1186/1471-2105-14-101.Peer-Reviewed Original ResearchConceptsGaussian mixture decompositionFalse discoveriesMicroarray gene expression dataNon-informative genesAdaptive filteringSample meanAdaptive methodSample varianceGaussian componentsMixture decompositionGene filteringEarlier paperGene expression dataFilteringOptimal threshold valuePrevious methodsMicroarray experimentsNew methodTwo-step procedureThreshold valueCorrection methodPower of detectionImportant parametersSecond stepMicroarray data