2023
Short- and long-term effects of radiation exposure at low dose and low dose rate in normal human VH10 fibroblasts
Akuwudike P, López-Riego M, Marczyk M, Kocibalova Z, Brückner F, Polańska J, Wojcik A, Lundholm L. Short- and long-term effects of radiation exposure at low dose and low dose rate in normal human VH10 fibroblasts. Frontiers In Public Health 2023, 11: 1297942. PMID: 38162630, PMCID: PMC10755029, DOI: 10.3389/fpubh.2023.1297942.Peer-Reviewed Original ResearchMeSH KeywordsDose-Response Relationship, RadiationFibroblastsGamma RaysHumansRadiation ExposureRadiation, IonizingConceptsLong-term effectsLow dosesDose-rate effectiveness factorLow dose rateSignificant early effectsColony forming assaysDays post irradiationEarly time pointsPooled cohortValidation cohortStrong cytotoxic effectEpidemiological dataLow doseGy/minCell growth curveSample cohortCohortThird cohortCell viability assaysRadiation exposureEarly effectsTime pointsCytotoxic effectsGene expression changesConsistent upregulation
2014
Radiation-induced Changes in Levels of Selected Proteins in Peripheral Blood Serum of Breast Cancer Patients as a Potential Triage Biodosimeter for Large-scale Radiological Emergencies
Deperas-Kaminska M, Bajinskis A, Marczyk M, Polanska J, Wersäll P, Lidbrink E, Ainsbury EA, Guipaud O, Benderitter M, Haghdoost S, Wojcik A. Radiation-induced Changes in Levels of Selected Proteins in Peripheral Blood Serum of Breast Cancer Patients as a Potential Triage Biodosimeter for Large-scale Radiological Emergencies. Health Physics 2014, 107: 555-563. PMID: 25353241, DOI: 10.1097/hp.0000000000000158.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBiomarkersBlood ProteinsBreast NeoplasmsDose-Response Relationship, RadiationEmergenciesEnzyme-Linked Immunosorbent AssayFemaleHumansMiceRadiation InjuriesRadiation MonitoringRadiometryTriageConceptsPeripheral blood serumBreast cancer patientsLarge-scale radiological emergencyCancer patientsApolipoprotein EConsistent dose-response relationshipBlood serumExternal beam radiotherapyIrradiation of skinKinase 4Dose-response relationshipLogistic regression modelsPartial-body exposuresPurpose of triageMultinomial logistic regression modelsBeam radiotherapyBlood samplesFetuin BMultivariate analysisBody exposureDifferent dosesRadiation-induced changesSerumProtein 7Factor X