2023
Combining Low-Dose Computer-Tomography-Based Radiomics and Serum Metabolomics for Diagnosis of Malignant Nodules in Participants of Lung Cancer Screening Studies
Zyla J, Marczyk M, Prazuch W, Sitkiewicz M, Durawa A, Jelitto M, Dziadziuszko K, Jelonek K, Kurczyk A, Szurowska E, Rzyman W, Widłak P, Polanska J. Combining Low-Dose Computer-Tomography-Based Radiomics and Serum Metabolomics for Diagnosis of Malignant Nodules in Participants of Lung Cancer Screening Studies. Biomolecules 2023, 14: 44. PMID: 38254644, PMCID: PMC10813699, DOI: 10.3390/biom14010044.Peer-Reviewed Original ResearchSerum metabolomicsComputed tomography lung cancer screeningLow-dose computed tomography (LDCT) lung cancer screeningLung cancer screening studyTomography lung cancer screeningLung cancer screeningCancer screening studyLung cancer diagnosisCollected cohortCancer screeningLung cancerSerum metabolomeBenign lesionsPulmonary nodulesMetabolomic evaluationAuxiliary biomarkerLogistic regressionDiagnosisCancer diagnosisLung nodulesMalignant nodulesScreening studyPatientsRadiomicsMolecular features
2016
Serum mass profile signature as a biomarker of early lung cancer
Widlak P, Pietrowska M, Polanska J, Marczyk M, Ros-Mazurczyk M, Dziadziuszko R, Jassem J, Rzyman W. Serum mass profile signature as a biomarker of early lung cancer. Lung Cancer 2016, 99: 46-52. PMID: 27565913, DOI: 10.1016/j.lungcan.2016.06.011.Peer-Reviewed Original ResearchConceptsEarly lung cancerLung cancerNegative predictive valuePredictive valueComputed tomographyEarly-stage lung cancerLow-dose computed tomographyIndeterminate pulmonary nodulesStage lung cancerPotential clinical usefulnessPositive predictive valueValidation cohortHealthy controlsClinical usefulnessDiscovery cohortBlood samplesIndependent cohortWeight serum fractionsPulmonary nodulesIndependent sample setCancerPatientsHealthy participantsMolecular biomarkersCohort