2013
Influence of Alcohol Use on Neural Response to Go/No-Go Task in College Drinkers
Ahmadi A, Pearlson GD, Meda SA, Dager A, Potenza MN, Rosen R, Austad CS, Raskin SA, Fallahi CR, Tennen H, Wood RM, Stevens MC. Influence of Alcohol Use on Neural Response to Go/No-Go Task in College Drinkers. Neuropsychopharmacology 2013, 38: 2197-2208. PMID: 23670589, PMCID: PMC3773670, DOI: 10.1038/npp.2013.119.Peer-Reviewed Original ResearchConceptsSupplementary motor areaHeavy drinkersLight drinkersCollege-age drinkersAlcohol useResponse inhibitionBlood oxygen level-dependent (BOLD) responseHeavy alcohol drinkersImportant risk factorBilateral middle frontal gyrusAlcohol use disorderBrain activityAnterior cingulate cortexGreater BOLD responseLevel-dependent responsesMiddle frontal gyrusSuperior temporal gyrusImpaired response inhibitionAlcohol drinkersRisk factorsResponse inhibition taskRight hippocampusMotor areaWarrants additional investigationBilateral parietal lobules
2012
Examining the effect of psychopathic traits on gray matter volume in a community substance abuse sample
Cope LM, Shane MS, Segall JM, Nyalakanti PK, Stevens MC, Pearlson GD, Calhoun VD, Kiehl KA. Examining the effect of psychopathic traits on gray matter volume in a community substance abuse sample. Psychiatry Research 2012, 204: 91-100. PMID: 23217577, PMCID: PMC3536442, DOI: 10.1016/j.pscychresns.2012.10.004.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntisocial Personality DisorderBrainCognition DisordersFemaleHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedNerve Fibers, MyelinatedNeuropsychological TestsPersonality InventoryPsychiatric Status Rating ScalesRegression AnalysisResidence CharacteristicsSubstance-Related DisordersConceptsGray matter volumeMatter volumeOrbital frontal cortexMagnetic resonance imagingRight hippocampusFrontal cortexBilateral orbital frontal cortexRight anterior cingulateGray matter reductionsGray matter increasesStructural imaging studiesLimbic regionsBrain abnormalitiesRight insulaParalimbic regionsAnterior cingulateLifetime drugSubstance abuse sampleResonance imagingImaging studiesAlcohol useExploratory regression analysisRegression analysisLimbicMatter reduction