2023
Inherited and Acquired Thrombophilias
Abhari P, Paidas M. Inherited and Acquired Thrombophilias. 2023, 114-122. DOI: 10.1002/9781119636540.ch14.Peer-Reviewed Original ResearchThrombophilic conditionsTransient hypercoagulable stateCoagulation factor levelsContext of pregnancyAcquired ThrombophiliaAntifibrinolytic systemsNeonatal outcomesProthrombotic tendencyHypercoagulable stateHormonal changesClinical consequencesThrombotic conditionsFactor levelsPregnancyThrombophiliaMaternalDiagnosis
2020
Can Recurrent Pregnancy Loss Be Prevented by Antithrombotic Agents?
Merriam A, Paidas M. Can Recurrent Pregnancy Loss Be Prevented by Antithrombotic Agents? 2020, 223-230. DOI: 10.1201/9780429450303-24.ChaptersRecurrent pregnancy lossPregnancy outcomesAntiplatelet agentsPregnancy lossAntithrombotic agentsMultiple adverse pregnancy outcomesSmall case-control studyAntiplatelet agent aspirinAdverse pregnancy outcomesSuccessful pregnancy outcomeCase-control studyMultiple prospective studiesHistory of thrombophiliaClass of drugsEffects of anticoagulantsAspirin treatmentProspective studyAnticoagulant agentsLive birthsThrombophiliaBlood clotsWomenAspirinOutcomesAgents
2016
Thrombophilia and Pregnancy
Hendrix P, Tinelli A, Malvasi A, Paidas M. Thrombophilia and Pregnancy. 2016, 287-313. DOI: 10.1007/978-3-319-31377-1_13.Peer-Reviewed Original ResearchAdverse pregnancy outcomesPregnancy outcomesHereditary thrombophiliaBest practice clinical guidelinesContinuum of pregnancyVenous thromboembolic eventsRecurrent fetal lossIntrauterine growth restrictionProthrombin gene mutationNatural anticoagulant protein SFactor V LeidenEfficacy of preventionFetal morbidityThromboembolic eventsAntiphospholipid syndromeMaternal riskPuerperal periodClinical guidelinesFetal lossGrowth restrictionTreatment paradigmV LeidenRisk associationThrombophiliaPregnancy
2012
Inherited and Acquired Thrombophilias
Paidas M. Inherited and Acquired Thrombophilias. 2012, 108-120. DOI: 10.1002/9781119963783.ch15.Peer-Reviewed Original ResearchAntiphospholipid antibody syndromePlacenta-mediated complicationsAntibody syndromeThrombophilic conditionsProthrombin G20210A gene mutationFactor V Leiden mutationBenefits of anticoagulationCornerstone of treatmentProspective cohort studyRecurrent pregnancy lossAdequate clinical trialsV Leiden mutationAcquired ThrombophiliaAntiplatelet therapyCohort studyPregnancy lossThrombophilic mutationsClinical trialsLeiden mutationNatural anticoagulantsRoutine useThrombophiliaGene mutationsAnticoagulationComplications
2011
Thrombophilia and the Placenta
Han C, Paidas M. Thrombophilia and the Placenta. 2011, 253-260. DOI: 10.1002/9781444393927.ch33.Peer-Reviewed Original Research
2010
Inherited and Acquired Thrombophilia in Obstetrics
Paidas M, Han C, Hossain N, Lockwood C. Inherited and Acquired Thrombophilia in Obstetrics. 2010, 67-110. DOI: 10.1002/9781444328332.ch5.Peer-Reviewed Original ResearchThrombophilias and Pregnancy
Rodger M, Paidas M, Tsen L, Douglas J. Thrombophilias and Pregnancy. 2010, 101-117. DOI: 10.1002/9781444323016.ch4.Peer-Reviewed Original Research
2007
Do Thrombophilias Cause Placenta-Mediated Pregnancy Complications?
Rodger M, Paidas M. Do Thrombophilias Cause Placenta-Mediated Pregnancy Complications? Seminars In Thrombosis And Hemostasis 2007, 33: 597-603. PMID: 17768692, DOI: 10.1055/s-2007-985756.Peer-Reviewed Original ResearchConceptsPlacenta-mediated pregnancy complicationsPregnancy complicationsAnticoagulant prophylaxisIntrauterine growth restrictionThrombophilic pregnanciesNeonatal morbidityPlacental abruptionVenous thromboembolismThrombophilic womenPregnancy lossGrowth restrictionClinical consequencesHigh riskThrombophiliaComplicationsCausal associationProphylaxisAssociationThromboembolismAbruptionPreeclampsiaMorbidityEvidencePregnancyNew associationsThromboembolic Disorders of Pregnancy
Paidas M, Pettker C, Lockwood C. Thromboembolic Disorders of Pregnancy. 2007, 825-848. DOI: 10.1002/9780470753293.ch47.ChaptersRecurrent adverse pregnancy outcomesAdverse pregnancy outcomesVenous thromboembolismPregnancy outcomesPregnancy treatmentPregnancy managementRisk factorsRadiation exposureAnemia risk factorsThromboembolic disordersAnticoagulationThromboembolismPregnancyThrombophiliaSurgeryDiagnosisPharmacologyWomenOutcomesTreatmentExposure
2006
Inherited Thrombophilias and Early Pregnancy Loss
Langhoff-Roos J, Paidas M, Ku D, Arkel Y, Loekwood C. Inherited Thrombophilias and Early Pregnancy Loss. Medical Intelligence Unit 2006, 229-243. DOI: 10.1007/0-387-34944-8_20.Peer-Reviewed Original ResearchFactor V LeidenThrombophilic conditionsPregnancy complicationsClinical manifestationsV LeidenFirst trimester pregnancy outcomeHeterozygous factor V LeidenIntrauterine growth restrictionLate fetal lossEarly pregnancy lossMaternal thromboembolismThrombogenic mutationsAbruptio placentaePregnancy outcomesProthrombotic conditionsPregnancy lossFetal lossGrowth restrictionAntithrombin deficiencyClinical practiceHeterogeneous groupComplicationsThrombophiliaDominant conditionCurrent knowledge
2005
Protein Z, protein S levels are lower in patients with thrombophilia and subsequent pregnancy complications
PAIDAS MJ, KU D, LEE M, MANISH S, THURSTON A, LOCKWOOD CJ, ARKEL YS. Protein Z, protein S levels are lower in patients with thrombophilia and subsequent pregnancy complications. Journal Of Thrombosis And Haemostasis 2005, 3: 497-501. PMID: 15748239, DOI: 10.1111/j.1538-7836.2005.01158.x.Peer-Reviewed Original ResearchConceptsAdverse pregnancy outcomesNormal pregnancy outcomeProtein S levelsPZ levelsPregnancy outcomesProtein SSubsequent pregnancy complicationsProtein ZAdditional risk factorsFree PS antigenPregnancy complicationsPregnant controlsThird trimesterPlasma levelsRisk factorsPatientsThrombophiliaPS antigenS levelsWomenSignificant decreasePS levelsOutcomesLow levelsTrimester
2004
Pregnant patients with thrombophilia and subsequent adverse pregnancy outcomes have a decreased first trimester response to thrombomodulin in an activated partial thromboplastin time (APTT) system
Paidas M, Ku D, Lee M, Lockwood C, Arkel Y. Pregnant patients with thrombophilia and subsequent adverse pregnancy outcomes have a decreased first trimester response to thrombomodulin in an activated partial thromboplastin time (APTT) system. Journal Of Thrombosis And Haemostasis 2004, 2: 840-841. PMID: 15099295, DOI: 10.1111/j.1538-7836.2004.00680.x.Peer-Reviewed Original Research