2024
Venous Thromboembolism Prophylaxis in Pregnancy: Why are the U.S. and European Guidelines so Different? Recent Studies and Clinical Insights
Piacquadio M, Paidas M. Venous Thromboembolism Prophylaxis in Pregnancy: Why are the U.S. and European Guidelines so Different? Recent Studies and Clinical Insights. Current Obstetrics And Gynecology Reports 2024, 14: 3. DOI: 10.1007/s13669-024-00407-9.Peer-Reviewed Original ResearchLow-molecular-weight heparinVenous thromboembolism prophylaxisVenous thromboembolismObstetric patientsEuropean guidelinesPostpartum periodHospitalized obstetric patientsMolecular weight heparinMechanical VTE prophylaxisVTE risk stratificationRandomized controlled studyObstetric populationPregnant populationRisk stratificationThromboembolism prophylaxisVTE prophylaxisInstitutional protocolMechanical prophylaxisWeight heparinProphylaxisAnticoagulant agentsPregnancyPoor adherenceControlled studiesPatientsThe Necessity of Type and Screen Result Prior to Proceeding to Operating Room for Scheduled Cesarean Delivery in a Low Hemorrhage Risk Population [ID 2683392]
Hoffmann E, Druyan B, Fletcher M, Ridore M, Paidas M, Toledo P. The Necessity of Type and Screen Result Prior to Proceeding to Operating Room for Scheduled Cesarean Delivery in a Low Hemorrhage Risk Population [ID 2683392]. Obstetrics And Gynecology 2024, 143: 52s-53s. DOI: 10.1097/01.aog.0001013676.39387.ba.Peer-Reviewed Original ResearchScheduled cesarean deliveryCesarean deliveryBlood transfusionHemorrhage scoreOperating roomIRB-approved retrospective cohort studyTime of blood transfusionTransfused intra-operativelyRetrospective cohort studyChart reviewIntra-operativelyPhysician dissatisfactionCohort studyTransfusionRisk populationPatientsOR delaysBloodScreening resultsScoresMandatory typeDeliveryFinancial ramificationsScreeningHemorrhageSpeculum-free portable preterm imaging system
Boonya-Ananta T, Gonzalez M, Ajmal A, Du Le V, DeHoog E, Paidas M, Jayakumar A, Ramella-Roman J. Speculum-free portable preterm imaging system. Journal Of Biomedical Optics 2024, 29: 052918-052918. PMID: 38282917, PMCID: PMC10821769, DOI: 10.1117/1.jbo.29.5.052918.Peer-Reviewed Original ResearchConceptsNon-pregnant volunteersWeeks of gestationMortality rateNon-pregnant cervixCervical imagesPreterm birth riskStandard of careMaternal mortality rateUterine cervixPreterm birthPremature birthWomen's reproductive healthBirth riskCervixQuality of lifeDevelopmental impairmentReproductive healthBirthPatientsInfantsInfant mortality rateReducing infantInsertion sheathImaging probesPatient care
2023
Prior viral infection determines the mode and severity of monkeypox virus
Hussain H, Paidas M, Fadel A, Ramamoorthy R, Garcia E, Saadoon Z, Casmartino E, Mendez L, Williams E, Ruiz-Cordero R, Jayakumar A. Prior viral infection determines the mode and severity of monkeypox virus. International Journal Of Infectious Diseases 2023, 131: 95-99. PMID: 37001797, PMCID: PMC10060859, DOI: 10.1016/j.ijid.2023.03.047.Peer-Reviewed Original ResearchConceptsViral infectionHistory of HCVPrior viral infectionProdrome phaseSystemic complicationsCutaneous changesClinical presentationSkin findingsPathological characteristicsPrior infectionHistopathological analysisMonkeypox virusInfectionSkin architectureZoonotic virusesPatientsVirusSeveritySpecific microbesGenus OrthopoxvirusHCVComplicationsHIVHumansMPOX
2022
Cervical length and risk of unplanned cesarean hysterectomy in patients with placenta accreta-previa spectrum
Santos J, Rodriguez S, Saad A, Yasin S, Castillo-Acosta R, Gali J, Huang M, Paidas M, Ghulmiyyah L, Sfakianaki A. Cervical length and risk of unplanned cesarean hysterectomy in patients with placenta accreta-previa spectrum. American Journal Of Obstetrics And Gynecology 2022, 226: s266. DOI: 10.1016/j.ajog.2021.11.452.Peer-Reviewed Original Research
2021
1034 Are socioeconomically disadvantaged pregnant patients disproportionally infected by SARS-CoV-2 virus?
Ndubizu C, Colon-Aponte C, Galli J, Lebron C, Cohen M, Cruz N, Covarrubias A, Ahn H, Abhari P, Pallikkuth S, Potter J, Spiliopoulos M, Saad A, Pahwa S, Jayakumar A, Burkett G, Duara S, Bandstra E, Paidas M, Sfakianaki A. 1034 Are socioeconomically disadvantaged pregnant patients disproportionally infected by SARS-CoV-2 virus? American Journal Of Obstetrics And Gynecology 2021, 224: s641. PMCID: PMC7848529, DOI: 10.1016/j.ajog.2020.12.1059.Peer-Reviewed Original Research
2013
347: Recombinant human antithrombin (rhAT) for prevention of venous thromboembolism (VTE) in pregnant patients with hereditary antithrombin deficiency (HD)
Paidas M, Triche E, James A, Ballard T, Lowry S. 347: Recombinant human antithrombin (rhAT) for prevention of venous thromboembolism (VTE) in pregnant patients with hereditary antithrombin deficiency (HD). American Journal Of Obstetrics And Gynecology 2013, 208: s154. DOI: 10.1016/j.ajog.2012.10.512.Peer-Reviewed Original Research
2010
Disseminated Intravascular Coagulation
Hossain N, Paidas M. Disseminated Intravascular Coagulation. 2010, 182-194. DOI: 10.1002/9781444328332.ch10.Peer-Reviewed Original ResearchDisseminated intravascular coagulationIntravascular coagulationEndothelial damageBlood productsAmniotic fluid embolismTransfusion of bloodAbruptio placentaeObstetric patientsHemorrhagic shockSystemic activationPrimary disorderFluid balanceIntravascular thrombiCoagulation factorsMultidisciplinary approachPregnancyPatientsObstetricsCoagulationBloodDisordersCorrect useLaboratory assaysConsequences of consumptionCoagulopathy
2005
Thrombophilic patients demonstrate progressive increases in vascoactivity compared to normal pregnancy
Urban G, Di Iorio R, Marinoni E, Ku D, Arkel Y, Paidas M. Thrombophilic patients demonstrate progressive increases in vascoactivity compared to normal pregnancy. American Journal Of Obstetrics And Gynecology 2005, 193: s176. DOI: 10.1016/j.ajog.2005.10.707.Peer-Reviewed Original ResearchProtein Z, protein S levels are lower in patients with thrombophilia and subsequent pregnancy complications
PAIDAS MJ, KU D, LEE M, MANISH S, THURSTON A, LOCKWOOD CJ, ARKEL YS. Protein Z, protein S levels are lower in patients with thrombophilia and subsequent pregnancy complications. Journal Of Thrombosis And Haemostasis 2005, 3: 497-501. PMID: 15748239, DOI: 10.1111/j.1538-7836.2005.01158.x.Peer-Reviewed Original ResearchConceptsAdverse pregnancy outcomesNormal pregnancy outcomeProtein S levelsPZ levelsPregnancy outcomesProtein SSubsequent pregnancy complicationsProtein ZAdditional risk factorsFree PS antigenPregnancy complicationsPregnant controlsThird trimesterPlasma levelsRisk factorsPatientsThrombophiliaPS antigenS levelsWomenSignificant decreasePS levelsOutcomesLow levelsTrimester
2004
Pregnant patients with thrombophilia and subsequent adverse pregnancy outcomes have a decreased first trimester response to thrombomodulin in an activated partial thromboplastin time (APTT) system
Paidas M, Ku D, Lee M, Lockwood C, Arkel Y. Pregnant patients with thrombophilia and subsequent adverse pregnancy outcomes have a decreased first trimester response to thrombomodulin in an activated partial thromboplastin time (APTT) system. Journal Of Thrombosis And Haemostasis 2004, 2: 840-841. PMID: 15099295, DOI: 10.1111/j.1538-7836.2004.00680.x.Peer-Reviewed Original Research
2002
The use of coagulation activation markers (soluble fibrin polymer, TpPTM, prothrombin fragment 1.2, thrombin–antithrombin, and D-dimer) in the assessment of hypercoagulability in patients with inherited and acquired prothrombotic disorders
Arkel Y, Paidas M, Ku D. The use of coagulation activation markers (soluble fibrin polymer, TpPTM, prothrombin fragment 1.2, thrombin–antithrombin, and D-dimer) in the assessment of hypercoagulability in patients with inherited and acquired prothrombotic disorders. Blood Coagulation & Fibrinolysis 2002, 13: 199-205. PMID: 11943933, DOI: 10.1097/00001721-200204000-00005.Peer-Reviewed Original ResearchMeSH KeywordsActivated Protein C ResistanceAdolescentAdultAgedAged, 80 and overAntiphospholipid SyndromeAntithrombin IIIAntithrombin III DeficiencyAutoimmune DiseasesBiomarkersEnzyme-Linked Immunosorbent AssayFactor VFemaleFibrinFibrin Fibrinogen Degradation ProductsHumansHyperhomocysteinemiaMaleMiddle AgedPeptide FragmentsPeptide HydrolasesProtein C DeficiencyProtein S DeficiencyProthrombinRiskSolubilityThrombophiliaConceptsCoagulation activation markersActivation markersAssessment of hypercoagulabilityPercentage of patientsProthrombotic disordersVascular eventsConsecutive patientsThrombophilic abnormalitiesThrombotic riskPatientsSoluble fibrin polymersTPP levelsMean levelsMarkersAbnormalitiesFibrin polymersHypercoagulability
2001
173 Fetal fibronectin is a valid predictor of spontaneous preterm delivery in patients with cervical cerclages
Rebarber A, Sfakianaki A, Kuczynski E, Paidas M, Russo K, Maturi J, Roshanfekr D, Lockwood C. 173 Fetal fibronectin is a valid predictor of spontaneous preterm delivery in patients with cervical cerclages. American Journal Of Obstetrics And Gynecology 2001, 185: s128. DOI: 10.1016/s0002-9378(01)80208-8.Peer-Reviewed Original Research17 First trimester thrombus precursor protein (TPP) predicts adverse pregnancy outcome in thrombophilic patients
Paidas M, Urban G, Ku W, Arkel Y, Dilley A, Andrei R, Kuczynski E, Jeanine M, Mignosa M, Khan S, Schoenfeld J, Lockwood C. 17 First trimester thrombus precursor protein (TPP) predicts adverse pregnancy outcome in thrombophilic patients. American Journal Of Obstetrics And Gynecology 2001, 185: s76. DOI: 10.1016/s0002-9378(01)80027-2.Peer-Reviewed Original Research
2000
Change in Cervical Length After Cerclage as a Predictor of Preterm Delivery
DIJKSTRA K, FUNAI E, O'NEILL L, REBARBER A, PAIDAS M, YOUNG B. Change in Cervical Length After Cerclage as a Predictor of Preterm Delivery. Obstetrics And Gynecology 2000, 96: 346-350. DOI: 10.1097/00006250-200009000-00006.Peer-Reviewed Original ResearchConceptsCervical lengthProphylactic cerclagePregnancy outcomesWeeks' gestationSerial cervical length measurementsMean cervical lengthMethods Eighty womenTransvaginal ultrasonographic evaluationCervical length measurementEarly third trimesterTransvaginal ultrasound examinationCerclage groupPreterm deliveryPreterm birthSerial followTerm deliveryPrimary physicianThird trimesterUltrasonographic evaluationUltrasound examinationCerclageMost womenPatientsGestationSignificant associationChange in cervical length after cerclage as a predictor of preterm delivery.
Dijkstra K, Funai E, O'Neill L, Rebarber A, Paidas M, Young B. Change in cervical length after cerclage as a predictor of preterm delivery. Obstetrics And Gynecology 2000, 96: 346-50. PMID: 10960624, DOI: 10.1016/s0029-7844(00)00924-8.Peer-Reviewed Original ResearchConceptsCervical lengthProphylactic cerclagePregnancy outcomesWeeks' gestationSerial cervical length measurementsMean cervical lengthTransvaginal ultrasonographic evaluationCervical length measurementEarly third trimesterTransvaginal ultrasound examinationCerclage groupPreterm deliveryPreterm birthSerial followTerm deliveryPrimary physicianThird trimesterUltrasonographic evaluationUltrasound examinationCerclageMost womenPatientsGestationSignificant associationLogistic regression
1999
Change in Cervical Length After Prophylactic Cerclage
FUNAI E, PAIDAS M, REBARBER A, O'NEILL L, ROSEN T, YOUNG B. Change in Cervical Length After Prophylactic Cerclage. Obstetrics And Gynecology 1999, 94: 117-119. DOI: 10.1097/00006250-199907000-00023.Peer-Reviewed Original ResearchConceptsCervical lengthInstitutional review boardProphylactic cerclageShirodkar sutureIncompetent cervixMethods PatientsTerm deliveryTransvaginal ultrasoundObservational studyResults TwentyPhysician preferenceReview boardMcDonald operationsCerclageFurther studiesMeasurable increaseShirodkarCervixPatientsChange in cervical length after prophylactic cerclage.
Funai E, Paidas M, Rebarber A, O'Neill L, Rosen T, Young B. Change in cervical length after prophylactic cerclage. Obstetrics And Gynecology 1999, 94: 117-9. PMID: 10389730, DOI: 10.1016/s0029-7844(98)00568-7.Peer-Reviewed Original Research