2005
Thrombophilic patients demonstrate progressive increases in vascoactivity compared to normal pregnancy
Urban G, Di Iorio R, Marinoni E, Ku D, Arkel Y, Paidas M. Thrombophilic patients demonstrate progressive increases in vascoactivity compared to normal pregnancy. American Journal Of Obstetrics And Gynecology 2005, 193: s176. DOI: 10.1016/j.ajog.2005.10.707.Peer-Reviewed Original Research
2004
Normal pregnancy is associated with the development of protein S and protein Z antibodies, independent of PS and PZ levels
Paidas M, Ku D, Arkel Y, Triche E, Fortunato C, Hamar B, Ku E, Lockwood C. Normal pregnancy is associated with the development of protein S and protein Z antibodies, independent of PS and PZ levels. American Journal Of Obstetrics And Gynecology 2004, 191: s140. DOI: 10.1016/j.ajog.2004.10.393.Peer-Reviewed Original ResearchTerm Decidual Cell Thrombomodulin and Endothelial Protein C Receptor Expression Is Upregulated by Thrombin Irrespective of Ovarian Hormonal Priming.
Paidas M, Ku D, Arkel Y, Tang C, Fortunato C, Lockwood C. Term Decidual Cell Thrombomodulin and Endothelial Protein C Receptor Expression Is Upregulated by Thrombin Irrespective of Ovarian Hormonal Priming. Blood 2004, 104: 1947. DOI: 10.1182/blood.v104.11.1947.1947.Peer-Reviewed Original ResearchAdverse pregnancy outcomesDecidual cellsExpression of TMReal-time PCRAddition of hirudinEndothelial protein C receptor expressionTime PCRIntrauterine growth restrictionPro-inflammatory processesMaternal-fetal interfaceTM protein expressionProtein C systemHormonal primingUteroplacental thrombosisWestern blot analysisAbruptio placentaeGeneration of APCCesarean sectionPregnancy outcomesNormal pregnancyProthrombotic milieuUncomplicated pregnanciesFetal interfaceGestational ageMedroxy progesteroneProtein S Free Antigen Levels and the Occurrence of IgG and IgM Antibodies to Protein S in Normal Pregnancy.
Arkel Y, Ku D, Paidas M, Fortunato C, Ku E, Lockwood C. Protein S Free Antigen Levels and the Occurrence of IgG and IgM Antibodies to Protein S in Normal Pregnancy. Blood 2004, 104: 3993. DOI: 10.1182/blood.v104.11.3993.3993.Peer-Reviewed Original ResearchAdverse pregnancy outcomesNormal pregnancyIgM antibodiesProtein SPS IgGAntigen levelsReference rangeFree PS antigen levelsEvaluation of thrombophiliaPS antigen levelsNon-pregnant controlsNumber of patientsNon-pregnant donorsNon-pregnant valuesOccurrence of IgGAnticardiolipin syndromeProthrombotic processesPregnancy patientsPregnancy outcomesAutoimmune diseasesTrimester samplesHemostatic systemImmune responseHigh riskPregnancyThe Occurrence of Antibodies to Components of the Natural Coagulation Inhibitor System, Protein Z and Protheombin in Normal Pregnancy.
Ku D, Arkel Y, Paidas M, Triche E, Huang S, Musto J, Lockwood C. The Occurrence of Antibodies to Components of the Natural Coagulation Inhibitor System, Protein Z and Protheombin in Normal Pregnancy. Blood 2004, 104: 3995. DOI: 10.1182/blood.v104.11.3995.3995.Peer-Reviewed Original ResearchNon-pregnant controlsAnti-PC IgMAdverse pregnancy outcomesNormal pregnancyIgM antibodiesPS IgGOccurrence of antibodiesAnticardiolipin syndromeProthrombotic processesPregnancy outcomesAntibody levelsMost pregnanciesAutoimmune diseasesAntibody responseIgG antibodiesHemostatic balanceImmune responseTrimesterCoagulation factorsChronic responsesPregnancyIgMIgGGestationAntibodiesElevated sEPCR and PAI-1 Levels, but Not sThrombomodulin Levels in Normal Pregnancy.
Arkel Y, Paidas M, Ku D, Triche E, Lam X, Ku E, Lockwood C. Elevated sEPCR and PAI-1 Levels, but Not sThrombomodulin Levels in Normal Pregnancy. Blood 2004, 104: 3996. DOI: 10.1182/blood.v104.11.3996.3996.Peer-Reviewed Original ResearchEndothelial protein C receptorAdverse pregnancy outcomesPro-inflammatory cytokinesNormal pregnancyProtein C systemDecidual cellsEndothelial cellsProtein SEndometrial decidual cellsNon-pregnant controlsProtein C receptorCell surface proteinsPlasminogen activator inhibitorCell-surface thrombomodulinPregnancy outcomesProthrombotic statePlasma thrombomodulinNP patientsEC damageSurface proteinsControl of thrombosisSTM levelsTrimester samplesPregnancyFibrinolytic system