2009
Involvement of human decidual cell-expressed tissue factor in uterine hemostasis and abruption
Lockwood C, Paidas M, Murk W, Kayisli U, Gopinath A, Huang S, Krikun G, Schatz F. Involvement of human decidual cell-expressed tissue factor in uterine hemostasis and abruption. Thrombosis Research 2009, 124: 516-520. PMID: 19720393, PMCID: PMC2787516, DOI: 10.1016/j.thromres.2009.07.017.Peer-Reviewed Original ResearchConceptsDecidual cellsTissue factorPlacental ischemiaTF expressionDecidual cell-expressed tissue factorCultured term decidual cellsAutocrine/paracrine fashionDecidual spiral arteriesDecidual vascular remodelingTerm decidual cellsUteroplacental blood flowMaternal-fetal interfaceAutocrine/paracrine mediatorsDecidual infiltrationHemostatic protectionUterine hemostasisDecidual hemorrhageExtracellular matrixSpiral arteriesFetal interfaceHuman pregnancyVascular injuryConductance vesselsSFlt-1Interleukin-8
2004
Term Decidual Cell Thrombomodulin and Endothelial Protein C Receptor Expression Is Upregulated by Thrombin Irrespective of Ovarian Hormonal Priming.
Paidas M, Ku D, Arkel Y, Tang C, Fortunato C, Lockwood C. Term Decidual Cell Thrombomodulin and Endothelial Protein C Receptor Expression Is Upregulated by Thrombin Irrespective of Ovarian Hormonal Priming. Blood 2004, 104: 1947. DOI: 10.1182/blood.v104.11.1947.1947.Peer-Reviewed Original ResearchAdverse pregnancy outcomesDecidual cellsExpression of TMReal-time PCRAddition of hirudinEndothelial protein C receptor expressionTime PCRIntrauterine growth restrictionPro-inflammatory processesMaternal-fetal interfaceTM protein expressionProtein C systemHormonal primingUteroplacental thrombosisWestern blot analysisAbruptio placentaeGeneration of APCCesarean sectionPregnancy outcomesNormal pregnancyProthrombotic milieuUncomplicated pregnanciesFetal interfaceGestational ageMedroxy progesterone