2016
Activity of the C. elegans egg-laying behavior circuit is controlled by competing activation and feedback inhibition
Collins KM, Bode A, Fernandez RW, Tanis JE, Brewer JC, Creamer MS, Koelle MR. Activity of the C. elegans egg-laying behavior circuit is controlled by competing activation and feedback inhibition. ELife 2016, 5: e21126. PMID: 27849154, PMCID: PMC5142809, DOI: 10.7554/elife.21126.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsChloride ChannelsCholineFeedback, PhysiologicalFemaleGene Expression RegulationLocomotionMotor NeuronsMuscle ContractionOptogeneticsOvipositionPeriodicityReceptors, Biogenic AmineSerotoninSexual Behavior, AnimalSignal TransductionTyramineConceptsPassage of eggsUnderlying neural circuitsUv1 neuroendocrine cellsCommand neuronsMuscle contractionNeural circuitsNeuroendocrine cellsRhythmic activityBehavior circuitsCircuit activityCentral pattern generatorCircuit functionBody bendsFeedback inhibitionSlow locomotionPattern generatorNeuronsActivityVulva
2015
RNA ligation in neurons by RtcB inhibits axon regeneration
Kosmaczewski SG, Han SM, Han B, Meyer B, Baig HS, Athar W, Lin-Moore AT, Koelle MR, Hammarlund M. RNA ligation in neurons by RtcB inhibits axon regeneration. Proceedings Of The National Academy Of Sciences Of The United States Of America 2015, 112: 8451-8456. PMID: 26100902, PMCID: PMC4500288, DOI: 10.1073/pnas.1502948112.Peer-Reviewed Original Research
1996
EGL-10 Regulates G Protein Signaling in the C. elegans Nervous System and Shares a Conserved Domain with Many Mammalian Proteins
Koelle M, Horvitz H. EGL-10 Regulates G Protein Signaling in the C. elegans Nervous System and Shares a Conserved Domain with Many Mammalian Proteins. Cell 1996, 84: 115-125. PMID: 8548815, DOI: 10.1016/s0092-8674(00)80998-8.Peer-Reviewed Original ResearchMeSH KeywordsAllelesAmino Acid SequenceAnimalsBase SequenceCaenorhabditis elegansCaenorhabditis elegans ProteinsConserved SequenceFungal ProteinsGene DosageGenes, HelminthGTP-Binding ProteinsMammalsMolecular Sequence DataMusclesMutationNervous SystemNervous System Physiological PhenomenaOvumProteinsRatsRGS ProteinsSerotoninSignal TransductionYeastsConceptsEGL-10G proteinsNematode C. elegansG protein signalingMammalian genesGOA-1Mammalian proteinsC. elegansConserved domainProtein signalingNegative regulatorNeurotransmitter signalingProteinSignalingDose-dependent mannerPathwaySst2pElegansYeastGenesNervous systemDose-dependent fashionRegulatorCertain periodic behaviorsActivity