2007
Developmental Homeostasis of Mouse Retinocollicular Synapses
Chandrasekaran AR, Shah RD, Crair MC. Developmental Homeostasis of Mouse Retinocollicular Synapses. Journal Of Neuroscience 2007, 27: 1746-1755. PMID: 17301182, PMCID: PMC6673732, DOI: 10.1523/jneurosci.4383-06.2007.Peer-Reviewed Original ResearchMeSH KeywordsAlpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic AcidAnimalsAnimals, NewbornBrain MappingExcitatory Amino Acid AgonistsHomeostasisMembrane PotentialsMiceMice, Inbred C57BLMice, KnockoutModels, BiologicalNeuronsN-MethylaspartateReceptors, NicotinicRetinaSuperior ColliculiSynapsesVisual CortexVisual PathwaysConceptsRetinal wavesBeta2-/- miceSpontaneous retinal wavesRetinal ganglion cellsWild-type miceActivity-dependent competitionFirst postnatal weekTotal integrated responseLarge retinal areasTotal synaptic inputNeuronal receptive fieldsReceptive fieldsGanglion cellsPerturbation of activitiesSynaptic transmissionPostnatal weekResponse homeostasisSynaptic inputsRetinal areaRetinal inputSuperior colliculusStrong synapsesVisual cortexMutant miceRetinotopic mapping
2003
Adenylyl cyclase I regulates AMPA receptor trafficking during mouse cortical 'barrel' map development
Lu HC, She WC, Plas DT, Neumann PE, Janz R, Crair MC. Adenylyl cyclase I regulates AMPA receptor trafficking during mouse cortical 'barrel' map development. Nature Neuroscience 2003, 6: 939-947. PMID: 12897788, DOI: 10.1038/nn1106.Peer-Reviewed Original ResearchConceptsLong-term depressionLong-term potentiationAMPA receptor traffickingThalamocortical synapsesBarrelless miceBarrel map formationSynaptic AMPAR traffickingAMPAR subunit GluR1Activity-dependent mechanismsReceptor traffickingAC1 activityFunctional AMPARsSurface GluR1Thalamocortical afferentsMap formationAdenylyl cyclase IBarrel mapSubunit GluR1Cortical map formationAMPAR traffickingProtein kinase A (PKA) activitySynapsesAdenylyl cyclaseMiceImmature state
1997
Silent Synapses during Development of Thalamocortical Inputs
Isaac J, Crair M, Nicoll R, Malenka R. Silent Synapses during Development of Thalamocortical Inputs. Neuron 1997, 18: 269-280. PMID: 9052797, DOI: 10.1016/s0896-6273(00)80267-6.Peer-Reviewed Original ResearchConceptsLong-term potentiationThalamocortical synapsesThalamocortical inputsSilent synapsesFunctional synapsesPostnatal day 8Rat somatosensory cortexActivity-dependent mechanismsActivity-dependent increaseEarly postnatal developmentSomatosensory cortexPostsynaptic activityTopographical projectionDay 8Postnatal developmentSynaptic connectionsSynaptic strengthSynapsesCortexSignificant proportionThalamusEarly developmentPotentiation
1996
[The development of rat somatosensory (barrel) cortex visualized by optical recording].
Kurotani T, Crair MC, Higashi S, Toyama K, Molnar Z. [The development of rat somatosensory (barrel) cortex visualized by optical recording]. Protein (Tokyo) 1996, 41: 758-65. PMID: 8787046.Peer-Reviewed Original Research