2009
Consequences of axon guidance defects on the development of retinotopic receptive fields in the mouse colliculus
Chandrasekaran AR, Furuta Y, Crair MC. Consequences of axon guidance defects on the development of retinotopic receptive fields in the mouse colliculus. The Journal Of Physiology 2009, 587: 953-963. PMID: 19153163, PMCID: PMC2673768, DOI: 10.1113/jphysiol.2008.160952.Peer-Reviewed Original ResearchConceptsSuperior colliculusMutant miceBone morphogenetic protein receptorRetinal ganglion cell axonsGuidance moleculesSpontaneous retinal wavesGanglion cell axonsSuperficial superior colliculusReceptive field propertiesRetinotopic receptive fieldsActivity-dependent factorsMore RGCsRetinocollicular projectionRetinal wavesEctopic projectionsVentral retinaCell axonsRetinotopic map formationAnatomical defectsAction potentialsActivity-dependent learning ruleSpontaneous wavesRetinaRGCsMice
2000
Neurotrophin-4/5 Alters Responses and Blocks the Effect of Monocular Deprivation in Cat Visual Cortex during the Critical Period
Gillespie D, Crair M, Stryker M. Neurotrophin-4/5 Alters Responses and Blocks the Effect of Monocular Deprivation in Cat Visual Cortex during the Critical Period. Journal Of Neuroscience 2000, 20: 9174-9186. PMID: 11124995, PMCID: PMC2412905, DOI: 10.1523/jneurosci.20-24-09174.2000.Peer-Reviewed Original ResearchConceptsDeprived eyeVisual cortexNT-4/5Monocular deprivationCritical periodIntrinsic signal optical imagingEarly postnatal lifeCat visual cortexCortical cellsNT-3Ocular dominancePostnatal lifeAlters responsesVisual stimulationCortexCorrelated activityHr exposureNeural responsesStimulus orientationEyesInfusionNeuronsDeprivationResponsePeriod
1998
The Role of Visual Experience in the Development of Columns in Cat Visual Cortex
Crair M, Gillespie D, Stryker M. The Role of Visual Experience in the Development of Columns in Cat Visual Cortex. Science 1998, 279: 566-570. PMID: 9438851, PMCID: PMC2453000, DOI: 10.1126/science.279.5350.566.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBrain MappingCatsMicroelectrodesPhotic StimulationVision, MonocularVision, OcularVisual CortexVisual PathwaysConceptsCortical mapsVisual cortexCat visual cortexPrimary visual cortexWeeks of ageTime course parallelContralateral eyeCerebral cortexCortical plasticityCortical neuronsOcular dominanceVisual deprivationPattern visionCortexWeeksEyesVisual experienceCritical periodCourse parallelCatsNeuronsResponse
1997
Relationship between the Ocular Dominance and Orientation Maps in Visual Cortex of Monocularly Deprived Cats
Crair M, Ruthazer E, Gillespie D, Stryker M. Relationship between the Ocular Dominance and Orientation Maps in Visual Cortex of Monocularly Deprived Cats. Neuron 1997, 19: 307-318. PMID: 9292721, DOI: 10.1016/s0896-6273(00)80941-1.Peer-Reviewed Original ResearchConceptsCortical plasticityVisual cortexSame stimulus orientationSingle-unit recordingsStimulus orientationDeprived eyeIntrinsic optical signalsMonocular deprivationOcular dominanceOcular dominance mapsSelective lossOrientation tuningClosed eyesCritical periodCortexEyesNeuronsFunctional mapsBrief periodCompelling evidenceKittens