2009
Long-Term Potentiation and Long-Term Depression in Experience-Dependent Plasticity
Crair M, Shah R. Long-Term Potentiation and Long-Term Depression in Experience-Dependent Plasticity. 2009, 561-570. DOI: 10.1016/b978-008045046-9.01213-4.Peer-Reviewed Original ResearchLong-term depressionExperience-dependent plasticityLong-term potentiationActivity-dependent developmentHebbian synaptic plasticitySynaptic mechanismsMammalian sensory systemsSomatosensory systemSynaptic plasticityTerm potentiationSynaptic homeostasisTiming-dependent plasticityMechanistic linkPotentiationDepressionSensory systemsPlasticityBrain
2008
Mechanisms of response homeostasis during retinocollicular map formation
Shah RD, Crair MC. Mechanisms of response homeostasis during retinocollicular map formation. The Journal Of Physiology 2008, 586: 4363-4369. PMID: 18617562, PMCID: PMC2614012, DOI: 10.1113/jphysiol.2008.157222.Peer-Reviewed Original ResearchConceptsResponse homeostasisSynaptic plasticityIntrinsic excitabilityRetinocollicular map formationActivity-dependent developmentMouse superior colliculusHomeostatic plasticity mechanismsTotal synaptic inputReceptive fieldsDifferent mutant miceVisual receptive fieldsStrength of synapsesDifferent cellular mechanismsHebbian synaptic plasticityNeuronal outputSynaptic inputsSuperior colliculusRunaway excitationSynaptic scalingMutant miceNeural circuitsFunctional connectivityIndividual neuronsHomeostatic mechanismsCellular mechanisms
2001
Barrel Cortex Critical Period Plasticity Is Independent of Changes in NMDA Receptor Subunit Composition
Lu H, Gonzalez E, Crair M. Barrel Cortex Critical Period Plasticity Is Independent of Changes in NMDA Receptor Subunit Composition. Neuron 2001, 32: 619-634. PMID: 11719203, DOI: 10.1016/s0896-6273(01)00501-3.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBrain MappingCritical Period, PsychologicalExcitatory Amino Acid AntagonistsExcitatory Postsynaptic PotentialsGene Expression Regulation, DevelopmentalLong-Term PotentiationMiceMice, Inbred C57BLMice, KnockoutNeuronal PlasticityPiperidinesQuinoxalinesReceptors, AMPAReceptors, N-Methyl-D-AspartateSomatosensory CortexSynapsesThalamusConceptsNMDA receptor subunit compositionReceptor subunit compositionSubunit compositionMouse somatosensory barrel cortexCritical periodNR2A knockout miceCritical period plasticitySomatosensory barrel cortexNMDAR subunit compositionCurrent kineticsAfferent innervationBarrel cortexNR2B subunitKnockout miceSynaptic plasticityNR2A subunitPlasticity windowSubunits