2008
Retinocollicular Synapse Maturation and Plasticity Are Regulated by Correlated Retinal Waves
Shah RD, Crair MC. Retinocollicular Synapse Maturation and Plasticity Are Regulated by Correlated Retinal Waves. Journal Of Neuroscience 2008, 28: 292-303. PMID: 18171946, PMCID: PMC6671137, DOI: 10.1523/jneurosci.4276-07.2008.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAlpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic AcidAnimalsAnimals, NewbornBehavior, AnimalDose-Response Relationship, RadiationElectric StimulationExcitatory Amino Acid AntagonistsIn Vitro TechniquesMiceMice, KnockoutNeuronal PlasticityN-MethylaspartatePatch-Clamp TechniquesQuinoxalinesReceptors, NicotinicRetinaSuperior ColliculiSynapsesSynaptic TransmissionVisual PathwaysConceptsFirst postnatal weekRetinal wavesPostnatal weekSynapse maturationAMPA/NMDA ratioRetinotopic map refinementSpontaneous retinal wavesNicotinic ACh receptorsSecond postnatal weekRetinocollicular synapsesSynapses decreasesPattern of activationNMDA ratioSynaptic strengtheningACh receptorsQuantal amplitudeRetinotopic map formationSuperior colliculusControl synapsesSynaptic changesCoincident activityPlasticity protocolsFirst weekBeta2 subunitWeeks
2007
Developmental Homeostasis of Mouse Retinocollicular Synapses
Chandrasekaran AR, Shah RD, Crair MC. Developmental Homeostasis of Mouse Retinocollicular Synapses. Journal Of Neuroscience 2007, 27: 1746-1755. PMID: 17301182, PMCID: PMC6673732, DOI: 10.1523/jneurosci.4383-06.2007.Peer-Reviewed Original ResearchMeSH KeywordsAlpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic AcidAnimalsAnimals, NewbornBrain MappingExcitatory Amino Acid AgonistsHomeostasisMembrane PotentialsMiceMice, Inbred C57BLMice, KnockoutModels, BiologicalNeuronsN-MethylaspartateReceptors, NicotinicRetinaSuperior ColliculiSynapsesVisual CortexVisual PathwaysConceptsRetinal wavesBeta2-/- miceSpontaneous retinal wavesRetinal ganglion cellsWild-type miceActivity-dependent competitionFirst postnatal weekTotal integrated responseLarge retinal areasTotal synaptic inputNeuronal receptive fieldsReceptive fieldsGanglion cellsPerturbation of activitiesSynaptic transmissionPostnatal weekResponse homeostasisSynaptic inputsRetinal areaRetinal inputSuperior colliculusStrong synapsesVisual cortexMutant miceRetinotopic mapping