2013
Laminar and Columnar Development of Barrel Cortex Relies on Thalamocortical Neurotransmission
Li H, Fertuzinhos S, Mohns E, Hnasko TS, Verhage M, Edwards R, Sestan N, Crair MC. Laminar and Columnar Development of Barrel Cortex Relies on Thalamocortical Neurotransmission. Neuron 2013, 79: 970-986. PMID: 24012009, PMCID: PMC3768017, DOI: 10.1016/j.neuron.2013.06.043.Peer-Reviewed Original ResearchConceptsThalamocortical neurotransmissionCortical developmentNeuronal differentiationGlutamatergic synaptic transmissionSuperficial cortical laminaeEarly cortical developmentActivity-dependent factorsThalamocortical neuronsSomatosensory cortexCortical cytoarchitectureCortical laminationSynaptic transmissionNeuronal activityCortical laminaeCytoarchitectonic criteriaExtrinsic activityNeurotransmissionCortical columnsMolecular cuesNeuronsMorphologic developmentLittle evidenceColumnar developmentGene expressionExtrinsic factors
2011
How do barrels form in somatosensory cortex?
Li H, Crair MC. How do barrels form in somatosensory cortex? Annals Of The New York Academy Of Sciences 2011, 1225: 119-129. PMID: 21534999, PMCID: PMC4700879, DOI: 10.1111/j.1749-6632.2011.06024.x.Peer-Reviewed Original Research
2006
Barrel Map Development Relies on Protein Kinase A Regulatory Subunit IIβ-Mediated cAMP Signaling
Inan M, Lu HC, Albright MJ, She WC, Crair MC. Barrel Map Development Relies on Protein Kinase A Regulatory Subunit IIβ-Mediated cAMP Signaling. Journal Of Neuroscience 2006, 26: 4338-4349. PMID: 16624954, PMCID: PMC6674004, DOI: 10.1523/jneurosci.3745-05.2006.Peer-Reviewed Original ResearchConceptsBarrel map formationLayer IV neuronsActivity-dependent developmentAMPA receptor functionCAMP/PKA-dependent pathwayLong-term potentiationThalamocortical synapsesThalamocortical afferentsTC synapsesThalamocortical synapseBarrel cortexPKA targetsBarrel patternCortical developmentPKA-dependent pathwayBrain circuitryPostsynaptic processesSynapse formationReceptor functionCAMP-dependent protein kinaseHebbian mechanismsDevelopmental increaseMiceSynapsesActivity-dependent models