1996
Economic assessment of platelet glycoprotein IIb/IIIa inhibition for prevention of ischemic complications of high-risk coronary angioplasty. EPIC Investigators.
Mark D, Talley J, Topol E, Bowman L, Lam L, Anderson K, Jollis J, Cleman M, Lee K, Aversano T, Untereker W, Davidson-Ray L, Califf R. Economic assessment of platelet glycoprotein IIb/IIIa inhibition for prevention of ischemic complications of high-risk coronary angioplasty. EPIC Investigators. Circulation 1996, 94: 629-35. PMID: 8772681, DOI: 10.1161/01.cir.94.4.629.Peer-Reviewed Original ResearchMeSH KeywordsAbciximabAgedAngioplastyAntibodies, MonoclonalAnticoagulantsAspirinBlood TransfusionCosts and Cost AnalysisDouble-Blind MethodFemaleHeparinHumansImmunoglobulin Fab FragmentsInfusions, IntravenousInjections, IntravenousMaleMiddle AgedMyocardial IschemiaPlatelet Aggregation InhibitorsPlatelet Glycoprotein GPIIb-IIIa ComplexRecurrenceStentsTreatment OutcomeUnited StatesConceptsHigh-risk coronary angioplastyC7E3 FabIschemic eventsCoronary angioplastyInitial hospitalizationPlatelet glycoprotein IIb/IIIa inhibitionGlycoprotein IIb/IIIa inhibitionIIb/IIIa inhibitionAggressive platelet inhibitionBaseline medical costsIschemic end pointsReduced ischemic eventsAcute ischemic eventsCost of therapyEPIC trialMajor bleedingBleeding episodesIschemic complicationsStandard carePlatelet inhibitionHospitalization ratesReceptor antibodiesHospital costsMedical costsMedicare fee
1995
Length of hospital stay and complications after percutaneous transluminal coronary angioplasty. Clinical and procedural predictors. Heparin Registry Investigators.
Wolfe M, Roubin G, Schweiger M, Isner J, Ferguson J, Cannon A, Cleman M, Cabin H, Leya F, Bonan R, Strony J, Adelman B, Bittl J. Length of hospital stay and complications after percutaneous transluminal coronary angioplasty. Clinical and procedural predictors. Heparin Registry Investigators. Circulation 1995, 92: 311-9. PMID: 7634443, DOI: 10.1161/01.cir.92.3.311.Peer-Reviewed Original ResearchConceptsPercutaneous transluminal coronary angioplastyLength of stayMultivessel coronary artery diseasePTCA complicationsCoronary artery diseaseTransluminal coronary angioplastyHospital stayUnstable anginaBaseline variablesAdvanced ageComplex lesionsArtery diseaseCoronary angioplastyLesion complexityNon-Q-wave myocardial infarctionIndividual baseline variablesBaseline risk factorsClinical risk scoreEmergency bypass surgeryProlonged hospital staySelection of patientsAbrupt vessel closureConventional balloon angioplastyAccess of patientsStrongest predictor