2008
Mucosal antibody responses in experimental hookworm infection
BUNGIRO RD, SUN T, HARRISON LM, SHOEMAKER CB, CAPPELLO M. Mucosal antibody responses in experimental hookworm infection. Parasite Immunology 2008, 30: 293-303. PMID: 18312503, DOI: 10.1111/j.1365-3024.2008.01023.x.Peer-Reviewed Original ResearchConceptsMucosal IgA responsesSystemic immune responsesIgA responsesImmune responseHookworm infectionInfected hamstersRobust systemic immune responseAncylostoma ceylanicum infectionExperimental hookworm infectionFecal IgA responsesParasite-specific IgAMucosal immune responsesMucosal antibody responsesIntestinal worm burdenExcretory-secretory productsMucosal antibodiesProtective immunityChallenge infectionSerum IgGAntibody responsePrimary infectionSecretory IgAHamster modelIntestinal mucosaWorm burden
2005
Detection of excretory/secretory coproantigens in experimental hookworm infection.
BUNGIRO RD, Cappello M. Detection of excretory/secretory coproantigens in experimental hookworm infection. American Journal Of Tropical Medicine And Hygiene 2005, 73: 915-20. PMID: 16282303, DOI: 10.4269/ajtmh.2005.73.915.Peer-Reviewed Original ResearchMeSH KeywordsAncylostomaAncylostomiasisAnimalsAntibodies, HelminthAntigens, HelminthCricetinaeDisease Models, AnimalEnzyme-Linked Immunosorbent AssayFecesHumansMesocricetusParasite Egg CountConceptsEnzyme-linked immunosorbent assayMolecular host-parasite interactionsFuture diagnostic methodsExcretory/secretoryFecal extractsImmunosorbent assayA. ceylanicum infectionExperimental hookworm infectionIntestinal worm burdenRabbit polyclonal IgG antibodyPolyclonal IgG antibodiesES proteinsDiagnostic methodsHookworm antigensDetectionHookworm infectionIgG antibodiesStool samplesWorm burdenDay 17Hamster serumCoproantigenFaecal eggMug/Degrees C.
1988
Induction of resistance to Schistosoma mansoni by immunization with subfractions of worms.
Knopf P, Goldberg M, Grossi C, Cappello M, Coulter S. Induction of resistance to Schistosoma mansoni by immunization with subfractions of worms. American Journal Of Tropical Medicine And Hygiene 1988, 38: 515-28. PMID: 3152780, DOI: 10.4269/ajtmh.1988.38.515.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodies, HelminthEnzyme-Linked Immunosorbent AssayImmunity, ActiveImmunizationImmunization, PassiveLiposomesMaleMiceRatsSchistosoma mansoniSchistosomiasis mansoniConceptsInfection 3 weeksSchistosoma mansoni infectionExposure of ratsInduction of resistanceGlutaraldehyde-fixed parasitesLive infectionMansoni infectionBooster injectionChallenge infectionNaive ratsImmunization protocolDifferent adjuvantsLow dosesDose sizeRatsSchistosoma mansoniPartial protectionInfectionMiceInjectionWeeksInductionSubfractionsParasitesBuffered saline