2008
The olfactory isoform of adenylyl cyclase (AC3) in the renal macula densa serves as a key regulator of glomerular filtration rate
Pluznick J, Zou D, Zhang X, Yan Q, Rodriguez‐Gil D, Eisner C, Wells E, Greer C, Schnermann J, Wang T, Firestein S, Caplan M. The olfactory isoform of adenylyl cyclase (AC3) in the renal macula densa serves as a key regulator of glomerular filtration rate. The FASEB Journal 2008, 22: 761.12-761.12. DOI: 10.1096/fasebj.22.1_supplement.761.12.Peer-Reviewed Original ResearchGlomerular filtration rateMacula densaTubuloglomerular feedbackFiltration rateEfferent arteriolar diametersRT-PCRPlasma renin concentrationRenal function studiesAdenylyl cyclaseWild-type littermatesOlfactory G-proteinOlfactory receptorsRenin concentrationRenin secretionArteriolar diameterOlfactory adenylyl cyclaseWestern blotMouse kidneyKidneyNon-olfactory tissuesRenal epitheliumG proteinsFunction studiesMiceKey regulator
2007
Functional Expression of Key Components of the Olfactory Receptor Signaling Pathway in the Distal Nephron
Pluznick J, Zhang X, Zou D, Yan Q, Wells E, Wang T, Firestein S, Caplan M. Functional Expression of Key Components of the Olfactory Receptor Signaling Pathway in the Distal Nephron. The FASEB Journal 2007, 21: a500-a500. DOI: 10.1096/fasebj.21.5.a500.Peer-Reviewed Original ResearchGlomerular filtration rateMouse kidneyRenal function studiesMacula densa cellsWild-type littermatesNormal mouse kidneyOlfactory G-proteinOlfactory receptorsReceptor Signaling PathwayRenal functionFiltration rateDistal tubulesDistal nephronKidneyWestern blotTubule segmentsRT-PCRAdenylyl cyclaseMiceNon-olfactory tissuesPotential roleG proteinsSignaling pathwaysFunction studiesMD cells
1987
Localization of Na+,K+-ATPase alpha-subunit to the sinusoidal and lateral but not canalicular membranes of rat hepatocytes.
Sztul ES, Biemesderfer D, Caplan MJ, Kashgarian M, Boyer JL. Localization of Na+,K+-ATPase alpha-subunit to the sinusoidal and lateral but not canalicular membranes of rat hepatocytes. Journal Of Cell Biology 1987, 104: 1239-1248. PMID: 3032985, PMCID: PMC2114466, DOI: 10.1083/jcb.104.5.1239.Peer-Reviewed Original ResearchConceptsAlpha-subunit bandsRat liver plasma membrane fractionsPlasma membraneAlpha subunitCatalytic activityMembrane fractionEntire plasma membranePlasma membrane fractionATPase alpha subunitIon-transporting epitheliaMonoclonal antibodiesWestern blotLiver plasma membrane fractionsBasolateral domainBasolateral distributionPolyclonal antibodies