2024
The association between female sex and depression following traumatic brain injury: A systematic review and meta-analysis
Sandhu M, Schonwald A, Boyko M, Jafar T, Freedman I, Woeste J, Kurup A, Funaro M, Zlotnik A, Gruenbaum S, Elsamadicy A, Reynolds R, Gruenbaum B. The association between female sex and depression following traumatic brain injury: A systematic review and meta-analysis. Neuroscience & Biobehavioral Reviews 2024, 168: 105952. PMID: 39603437, DOI: 10.1016/j.neubiorev.2024.105952.Peer-Reviewed Original ResearchPost-TBI depressionTraumatic brain injurySpectrum of TBI severityBrain injuryDiagnosis of depressionNeurobehavioral symptomsTBI severitySystematic reviewDepressionMeta-analysisStatistically significant differenceMedian ageFemale patientsPooled analysisFemale sexRisk factorsSevere casesParticipantsPotential associationSignificant differenceSexSeverityRiskInjurySubjects
2021
Absence seizures and their relationship to depression and anxiety: Evidence for bidirectionality
Gruenbaum BF, Sandhu MRS, Bertasi RAO, Bertasi TGO, Schonwald A, Kurup A, Gruenbaum SE, Freedman IG, Funaro MC, Blumenfeld H, Sanacora G. Absence seizures and their relationship to depression and anxiety: Evidence for bidirectionality. Epilepsia 2021, 62: 1041-1056. PMID: 33751566, PMCID: PMC8443164, DOI: 10.1111/epi.16862.Peer-Reviewed Original ResearchConceptsAbsence seizuresMood disordersChildhood epilepsyCommon manifestationInclusion criteriaEffective treatmentGenetic predispositionGreater oddsAnimal modelsAnatomical pathwaysSystematic reviewDepressionShort lossDisordersPatientsBidirectional relationshipSeizuresCurrent literatureAnxietySocial impairmentFurther researchReviewEpilepsyStrong correlationImpairment