2023
SMC5 Plays Independent Roles in Congenital Heart Disease and Neurodevelopmental Disability
O'Brien M, Pryzhkova M, Lake E, Mandino F, Shen X, Karnik R, Atkins A, Xu M, Ji W, Konstantino M, Brueckner M, Ment L, Khokha M, Jordan P. SMC5 Plays Independent Roles in Congenital Heart Disease and Neurodevelopmental Disability. International Journal Of Molecular Sciences 2023, 25: 430. PMID: 38203602, PMCID: PMC10779392, DOI: 10.3390/ijms25010430.Peer-Reviewed Original Research
2015
The NIMA-like kinase Nek2 is a key switch balancing cilia biogenesis and resorption in the development of left-right asymmetry
Endicott SJ, Basu B, Khokha M, Brueckner M. The NIMA-like kinase Nek2 is a key switch balancing cilia biogenesis and resorption in the development of left-right asymmetry. Development 2015, 142: 4068-4079. PMID: 26493400, PMCID: PMC4712839, DOI: 10.1242/dev.126953.Peer-Reviewed Original ResearchAnimalsBody PatterningCentriolesCiliaGene Expression Regulation, DevelopmentalGene Knockdown TechniquesHistone Deacetylase 6Histone DeacetylasesHomeodomain ProteinsHumansIntercellular Signaling Peptides and ProteinsMiceMicroscopy, FluorescenceMutationNIMA-Related KinasesNuclear Pore Complex ProteinsProtein Serine-Threonine KinasesRNA InterferenceSignal TransductionTranscription FactorsXenopusXenopus Proteins