2022
Imaging in the Intensive Care Unit
Toy D, Siegel M, Rubinowitz A. Imaging in the Intensive Care Unit. Seminars In Respiratory And Critical Care Medicine 2022, 43: 899-923. PMID: 36442475, DOI: 10.1055/s-0042-1750041.Peer-Reviewed Original ResearchConceptsICU patientsIll patientsPathologic disease statesInterstitial lung diseaseIntensive care unitCT pulmonary angiographySpecific clinical scenariosModality of choicePortable chest radiographsHospital courseRadiologic manifestationsCare unitPleural effusionPulmonary angiographyLung diseaseICU settingChest radiographsSmall pneumothoracesRadiographic examinationAdditional abnormalitiesPatientsClinical scenariosPatient careInvasive devicesDiagnostic accuracy
2020
Making Medical Treatment Decisions for Unrepresented Patients in the ICU. An Official American Thoracic Society/American Geriatrics Society Policy Statement
Pope TM, Bennett J, Carson SS, Cederquist L, Cohen AB, DeMartino ES, Godfrey DM, Goodman-Crews P, Kapp MB, Lo B, Magnus DC, Reinke LF, Shirley JL, Siegel MD, Stapleton RD, Sudore RL, Tarzian AJ, Thornton JD, Wicclair MR, Widera EW, White DB. Making Medical Treatment Decisions for Unrepresented Patients in the ICU. An Official American Thoracic Society/American Geriatrics Society Policy Statement. American Journal Of Respiratory And Critical Care Medicine 2020, 201: 1182-1192. PMID: 32412853, PMCID: PMC7233335, DOI: 10.1164/rccm.202003-0512st.Peer-Reviewed Original ResearchConceptsUnrepresented patientsFair processProcedural due processMedical treatment decisionsPolicy statementsElder lawDue processHealth lawProcedural safeguardsState lawsUndue influenceLawCritical care settingAppropriate balanceAdvance directivesEthical goalsTreatment decisionsAppropriate medical careDiligent searchCapacity assessmentPatient advocacyInstitutionsPolicy recommendationsLess oversightCare settings
2019
Evaluation of Swallow Function Post-Extubation: Is It Necessary to Wait 24 Hours?
Leder SB, Warner HL, Suiter DM, Young NO, Bhattacharya B, Siner JM, Davis KA, Maerz LL, Rosenbaum SH, Marshall PS, Pisani MA, Siegel MD, Brennan JJ, Schuster KM. Evaluation of Swallow Function Post-Extubation: Is It Necessary to Wait 24 Hours? Annals Of Otology Rhinology & Laryngology 2019, 128: 619-624. PMID: 30841709, DOI: 10.1177/0003489419836115.Peer-Reviewed Original ResearchConceptsIntensive care unitSwallow evaluationDifferent intensive care unitsRe-intubation rateYale Swallow ProtocolMajority of patientsPost-extubation dysphagiaIntubation durationNosocomial pneumoniaPost extubationLonger hospitalizationCare unitProspective InvestigationSwallow ProtocolSwallowingHoursDysphagiaHospitalizationIntubationPneumoniaPatientsIncidenceEvaluation
2017
Not “Out of Sight, Out of Mind”
Bournival N, Siegel MD, Akgün KM. Not “Out of Sight, Out of Mind”. Critical Care Medicine 2017, 45: 134-136. PMID: 27984282, DOI: 10.1097/ccm.0000000000002119.Peer-Reviewed Original Research
2015
Critical Care at the End of Life
Akgün KM, Kapo JM, Siegel MD. Critical Care at the End of Life. Seminars In Respiratory And Critical Care Medicine 2015, 36: 921-933. PMID: 26600274, DOI: 10.1055/s-0035-1565254.Peer-Reviewed Original ResearchMeSH KeywordsCommunicationCritical CareHumansIntensive Care UnitsPalliative CarePractice Guidelines as TopicTerminal CareConceptsPalliative care skillsPalliative care modelCare modelCare skillsBasic palliative care skillsComplex palliative care needsIntensive care unit admissionCare unit admissionPalliative care consultationPalliative care needsPalliative care domainsChronic life-limiting conditionsFamily-centered endLife-limiting conditionsPeer support groupsUnit admissionEnd of lifeICU patientsSymptom managementCare consultationsICU providersCritical careIndividual ICUsICUCare needsUse of the Blom Tracheotomy Tube with Suction Inner Cannula to Decontaminate Microorganisms from the Subglottic Space. A Proof of Concept
Rabach L, Siegel MD, Puchalski JT, Towle D, Follert M, Johnson KM, Rademaker AW, Leder SB. Use of the Blom Tracheotomy Tube with Suction Inner Cannula to Decontaminate Microorganisms from the Subglottic Space. A Proof of Concept. Annals Of The American Thoracic Society 2015, 12: 859-863. PMID: 25849332, DOI: 10.1513/annalsats.201501-010bc.Peer-Reviewed Original ResearchConceptsMechanical ventilationTracheotomy tubeSubglottic spaceInner cannulaNormal floraPulmonary complicationsSignificant reductionOngoing mechanical ventilationEndotracheal tube intubationSingle-center studyTube intubationIll patientsEndotracheal tubeICU adultsSputum samplesTracheotomyMicrobiologic analysisCannulaVentilationComplicationsWeeksPathogensDurationSupraTracheostomyAn Official American Thoracic Society Policy Statement: Managing Conscientious Objections in Intensive Care Medicine
Lewis-Newby M, Wicclair M, Pope T, Rushton C, Curlin F, Diekema D, Durrer D, Ehlenbach W, Gibson-Scipio W, Glavan B, Langer L, Manthous C, Rose C, Scardella A, Shanawani H, Siegel MD, Halpern SD, Truog RD, White DB. An Official American Thoracic Society Policy Statement: Managing Conscientious Objections in Intensive Care Medicine. American Journal Of Respiratory And Critical Care Medicine 2015, 191: 219-227. PMID: 25590155, DOI: 10.1164/rccm.201410-1916st.Peer-Reviewed Original ResearchMeSH KeywordsAccess to InformationAdolescentAdultAgedAttitude of Health PersonnelBioethical IssuesChildConscienceDisclosureFemaleGuidelines as TopicHealth Services AccessibilityHumansInfantIntensive Care UnitsMaleMiddle AgedOrganizational PolicyPatient RightsPregnancyProfessional AutonomySocieties, MedicalUnited StatesWorkforceConceptsCritical care settingCare settingsConscientious objectionMedical servicesAmerican Thoracic Society StatementIntensive care unit cliniciansMoral integrityTimely accessIntensive care medicineHospital administratorsMultidisciplinary expert committeeAvailable medical servicesPolicy statementsSociety statementCare medicineAdult medicineClinician judgmentPatient accessPatient advocacyCliniciansPatientsDiverse working groupExcessive hardshipsInstitutional mechanismsMoral dialogue
2013
Penguins and Palliative Care
Kapo J, Siegel MD. Penguins and Palliative Care. Critical Care Medicine 2013, 41: 2443-2444. PMID: 24060776, DOI: 10.1097/ccm.0b013e31829136f3.Peer-Reviewed Original ResearchAdvisory CommitteesDecision MakingHumansIntensive Care UnitsPalliative CareReferral and Consultation
2012
Palliative Care in the ICU
Nelson M, Azoulay P, Curtis JR, Mosenthal AC, Mulkerin CM, Puntillo K, Siegel MD. Palliative Care in the ICU. Journal Of Palliative Medicine 2012, 15: 168-174. PMID: 22280492, PMCID: PMC3388494, DOI: 10.1089/jpm.2011.9599.Peer-Reviewed Original Research
2011
The Management of the Critically Ill Obstetric Patient
Honiden S, Abdel-Razeq SS, Siegel MD. The Management of the Critically Ill Obstetric Patient. Journal Of Intensive Care Medicine 2011, 28: 93-106. PMID: 21841145, DOI: 10.1177/0885066611411408.Peer-Reviewed Original ResearchMeSH KeywordsCritical IllnessFemaleHumansIntensive Care UnitsMonitoring, PhysiologicObstetricsPregnancyPregnancy ComplicationsConceptsObstetric patientsCritically Ill Obstetric PatientIntensive care unit admissionIll obstetric patientsCare unit admissionCritical care physiciansMortality prediction toolProvision of careAcid-base statusUnit admissionHypertensive disordersICU mortalityMaternal outcomesRespiratory failureCesarean deliveryCommon indicationCare physiciansPostpartum hemorrhageCardiac arrestPhysiologic changesTreatment choicePatientsSpecial populationsRadiographic testsExposure limits
2010
Analytic Reviews: Managing the Agitated Patient in the ICU: Sedation, Analgesia, and Neuromuscular Blockade
Honiden S, Siegel MD. Analytic Reviews: Managing the Agitated Patient in the ICU: Sedation, Analgesia, and Neuromuscular Blockade. Journal Of Intensive Care Medicine 2010, 25: 187-204. PMID: 20663774, DOI: 10.1177/0885066610366923.Peer-Reviewed Original ResearchMeSH KeywordsAnalgesicsCritical IllnessDeliriumHumansHypnotics and SedativesIntensive Care UnitsPsychomotor AgitationSeverity of Illness IndexConceptsIntensive care unit physiciansICU lengthPharmacologic featuresVentilator daysCritical illnessMost patientsPharmacologic therapyIll patientsNeuroleptic medicationUnit physiciansNeuromuscular blockadeObjective assessment toolReversible etiologyPatient outcomesCognitive dysfunctionStructured protocolICU environmentPatientsPsychological distressAssessment toolDistressAnalgesiaUndertreatmentICUMedicationsThe Perception Gap Race, Religion, and Prognosis in the ICU
Siegel MD, Prigerson HG. The Perception Gap Race, Religion, and Prognosis in the ICU. CHEST Journal 2010, 138: 8-9. PMID: 20605808, DOI: 10.1378/chest.10-0454.Peer-Reviewed Original Research
2009
ELEVATED SERUM ANGIOPOIETIN 2 LEVELS ARE ASSOCIATED WITH INCREASED MORTALITY IN SEPSIS
Siner JM, Bhandari V, Engle KM, Elias JA, Siegel MD. ELEVATED SERUM ANGIOPOIETIN 2 LEVELS ARE ASSOCIATED WITH INCREASED MORTALITY IN SEPSIS. Shock 2009, 31: 348-353. PMID: 18791490, DOI: 10.1097/shk.0b013e318188bd06.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAngiopoietin-2APACHECritical CareFemaleHospital MortalityHumansIntensive Care UnitsLength of StayMaleMiddle AgedSepsisConceptsAng-2 levelsIntensive care unitAng-2Tertiary care medical intensive care unitProspective observational cohort studySerum Ang-2 levelsSerum angiopoietin-2 levelsMedical intensive care unitSerum Ang-2Observational cohort studyAngiopoietin-2 levelsIL-6 levelsHospital mortalityHuman sepsisICU admissionSevere sepsisCohort studyEndothelial dysfunctionHospital dischargeICU patientsIllness scoresSeptic shockCare unitIL-6Increased MortalityGlucose Control in the ICU — How Tight Is Too Tight?
Inzucchi SE, Siegel MD. Glucose Control in the ICU — How Tight Is Too Tight? New England Journal Of Medicine 2009, 360: 1346-1349. PMID: 19318385, DOI: 10.1056/nejme0901507.Peer-Reviewed Original Research