2021
The Crystalline Nephropathies
Perazella MA, Herlitz LC. The Crystalline Nephropathies. Kidney International Reports 2021, 6: 2942-2957. PMID: 34901567, PMCID: PMC8640557, DOI: 10.1016/j.ekir.2021.09.003.Peer-Reviewed Original ResearchAcute kidney injuryChronic kidney diseaseKidney injuryCrystalline nephropathyKidney diseaseCrystal depositionFurther kidney injuryIntrarenal crystal depositionUrinary sediment findingsUrine sediment examinationTubular obstructionHistologic findingsPathologic aspectsNephropathyClinical standpointInjuryTubular luminaSediment examinationFluid physiologyIdentification of crystalsCliniciansDiseaseIndirect cytotoxicityBiopsyInflammation
2020
Immune Checkpoint Inhibitors and Immune-Related Adverse Renal Events
Herrmann SM, Perazella MA. Immune Checkpoint Inhibitors and Immune-Related Adverse Renal Events. Kidney International Reports 2020, 5: 1139-1148. PMID: 32775813, PMCID: PMC7403510, DOI: 10.1016/j.ekir.2020.04.018.Peer-Reviewed Original ResearchImmune checkpoint inhibitorsAcute kidney injuryCheckpoint inhibitorsAdverse renal effectsAdverse renal eventsSubset of patientsPotential risk factorsAcute rejectionRenal eventsKidney injuryRenal effectsTransplant populationRenal toxicityRisk factorsBetter outcomesPatientsNephrotoxicityCliniciansCancer therapyCancerRecent studiesInhibitorsCurrent informationComplicationsProviders
2019
Diagnosing acute interstitial nephritis: considerations for clinicians
Nussbaum E, Perazella M. Diagnosing acute interstitial nephritis: considerations for clinicians. Clinical Kidney Journal 2019, 12: 808-813. DOI: 10.1093/ckj/sfz080.Peer-Reviewed Original ResearchAcute interstitial nephritisAcute kidney injuryAcute tubular necrosisInterstitial nephritisCommon causeDirect further managementKidney injuryMost patientsTubular necrosisKidney biopsyClinical historyFurther managementCliniciansLaboratory dataNephritisPatientsInjuryDiagnosisSingle testCauseBiopsyNecrosisBiomarkers
2015
The Urine Sediment as a Biomarker of Kidney Disease
Perazella MA. The Urine Sediment as a Biomarker of Kidney Disease. American Journal Of Kidney Diseases 2015, 66: 748-755. PMID: 25943719, DOI: 10.1053/j.ajkd.2015.02.342.Peer-Reviewed Original ResearchConceptsUrine sediment examinationKidney diseaseSediment examinationKidney conditionsUrine sedimentNovel urine biomarkersNew candidate biomarkersCentralized laboratory testingKidney injuryUrine biomarkersNew diagnostic technologiesUrinary biomarkersClinical practiceCandidate biomarkersTime-honored testsMaintenance of competencyDiagnostic panelDiagnostic testsDiseaseBiomarkersCliniciansUseful batteryExaminationDiagnostic informationDiagnostic technologies