Patients with atopic dermatitis have attenuated and distinct contact hypersensitivity responses to common allergens in skin
da Rosa J, Malajian D, Shemer A, Rozenblit M, Dhingra N, Czarnowicki T, Khattri S, Ungar B, Finney R, Xu H, Zheng X, Estrada YD, Peng X, Suárez-Fariñas M, Krueger JG, Guttman-Yassky E. Patients with atopic dermatitis have attenuated and distinct contact hypersensitivity responses to common allergens in skin. Journal Of Allergy And Clinical Immunology 2015, 135: 712-720. PMID: 25583101, DOI: 10.1016/j.jaci.2014.11.017.Peer-Reviewed Original ResearchConceptsAtopic dermatitisAllergic contact dermatitis reactionsBackground Atopic dermatitisContact hypersensitivity responseTh17/ILCommon contact allergensNon-AD groupAllergic immune reactionsAllergic contact dermatitisCommon inflammatory diseaseTissue immune responseContact dermatitis reactionsTh1 productsTh2 productsAllergen challengeImmune abnormalitiesAllergic sensitizationCommon allergensTh1 subsetContact sensitizationHypersensitivity responseInflammatory productsBiopsy specimensInflammatory diseasesContact allergens