2024
Carbapenem-resistant Enterobacterales in solid organ transplant recipients
Boutzoukas A, Dai W, Cober E, Abbo L, Komarow L, Chen L, Hill C, Satlin M, Grant M, Fries B, Patel G, McCarty T, Arias C, Bonomo R, van Duin D, Investigators F, Kanj S, Jabbour J, Zhang F, Lok J, Salata R, Di Castelnuovo V, Gutierrez J, Cober E, Richter S, Anderson D, Evans B, Hill C, Cross H, Baum K, Arias R, Fowler V, Ordoñez K, Jacob J, Li L, Kreiswirth B, Manca C, Chen L, Desai S, Herc E, Cordova E, Rioseco M, Vichez S, Sanchez M, Valderrama S, Figueroa J, Arias C, Dinh A, Panesso D, Rydell K, Tran T, Hu F, Su J, Jiang J, Wang M, Xu X, Yang Y, Munita J, Spencer M, Alenazi T, Bonomo R, Marshall S, Rudin S, Huskins C, Kerry, Patel R, Schmidt-Malan S, Revolinski S, Wortmann G, Kalayjian R, Weston G, Ostrowsky B, Patel G, Eiras D, Kim A, Garcia-Diaz J, Salcedo S, Farrell J, Liu Z, Henderson A, Paterson D, Xie Q, Kaye K, Gao H, Yu Y, Waters M, Fries B, Eilertson B, Marimuthu K, Chew K, Smitasin N, Tambyah P, Gallagher J, Peleg A, Leroi M, Li L, Komarow L, Ge L, Evans S, McCarty T, Chambers H, Garner O, Abbo L, van Duin D, Lautenbach E, Han J, Doi Y, Wong D, Hanson B, Reyes J, Botero M, Diaz L, Perez F, Banerjee R, Dhar S, Satlin M, Zong Z. Carbapenem-resistant Enterobacterales in solid organ transplant recipients. American Journal Of Transplantation 2024 PMID: 39522694, DOI: 10.1016/j.ajt.2024.10.020.Peer-Reviewed Original ResearchSolid organ transplant recipientsCarbapenem-resistant EnterobacteralesOrgan transplant recipientsTransplant recipientsCohort studyAll-cause 30-day mortalityStabilized inverse probabilityMatched cohort studyCarbapenem resistanceMalignancy historyClinical isolatesAdmitted from homeMatched patientsTransplant historyInfection criteriaAll-causeInverse probabilityMortality riskEnterobacteralesMortalityOutcomesRecipientsMalignancyMulticenterTransplantation
2020
Molecular and clinical epidemiology of carbapenem-resistant Enterobacterales in the USA (CRACKLE-2): a prospective cohort study
van Duin D, Arias C, Komarow L, Chen L, Hanson B, Weston G, Cober E, Garner O, Jacob J, Satlin M, Fries B, Garcia-Diaz J, Doi Y, Dhar S, Kaye K, Earley M, Hujer A, Hujer K, Domitrovic T, Shropshire W, Dinh A, Manca C, Luterbach C, Wang M, Paterson D, Banerjee R, Patel R, Evans S, Hill C, Arias R, Chambers H, Fowler V, Kreiswirth B, Bonomo R, Investigators M. Molecular and clinical epidemiology of carbapenem-resistant Enterobacterales in the USA (CRACKLE-2): a prospective cohort study. The Lancet Infectious Diseases 2020, 20: 731-741. PMID: 32151332, PMCID: PMC7473597, DOI: 10.1016/s1473-3099(19)30755-8.Peer-Reviewed Original ResearchConceptsCarbapenem-resistant EnterobacteralesCarbapenemase-producing EnterobacteralesCohort studyProspective cohort studyCRE infectionsIndex culturePrimary outcomeK pneumoniaeCRE groupAdmission ratesClinical dataClinical epidemiologyClinical culturesPatientsUS hospitalsDay 107Similar outcomesDisease controlDesirability of outcomeEnterobacteralesUnique isolatesNational InstituteOutcomesWhole-genome sequencingInfection