2022
Epidemiology of atrial fibrillation in the All of Us Research Program
Alonso A, Alam A, Kamel H, Subbian V, Qian J, Boerwinkle E, Cicek M, Clark C, Cohn E, Gebo K, Loperena-Cortes R, Mayo K, Mockrin S, Ohno-Machado L, Schully S, Ramirez A, Greenland P. Epidemiology of atrial fibrillation in the All of Us Research Program. PLOS ONE 2022, 17: e0265498. PMID: 35294480, PMCID: PMC8926244, DOI: 10.1371/journal.pone.0265498.Peer-Reviewed Original ResearchConceptsAtrial fibrillationNon-Hispanic whitesUs Research ProgramRisk factorsEpidemiology of AFIncidence of AFPresence of AFHigher body mass indexStudy of AFClinical risk factorsIncident atrial fibrillationCoronary heart diseaseBody mass indexElectronic health record dataMedical history dataMedical history surveyNon-Hispanic blacksHealth record dataAvailable EHR dataNon-Hispanic AsiansHeart failureStudy enrollmentMass indexEligible participantsMean age
2007
Risk-adjusted sequential probability ratio test control chart methods for monitoring operator and institutional mortality rates in interventional cardiology
Matheny M, Ohno-Machado L, Resnic F. Risk-adjusted sequential probability ratio test control chart methods for monitoring operator and institutional mortality rates in interventional cardiology. American Heart Journal 2007, 155: 114-120. PMID: 18082501, DOI: 10.1016/j.ahj.2007.08.022.Peer-Reviewed Original ResearchEffects of SVM parameter optimization on discrimination and calibration for post-procedural PCI mortality
Matheny M, Resnic F, Arora N, Ohno-Machado L. Effects of SVM parameter optimization on discrimination and calibration for post-procedural PCI mortality. Journal Of Biomedical Informatics 2007, 40: 688-697. PMID: 17600771, PMCID: PMC2170520, DOI: 10.1016/j.jbi.2007.05.008.Peer-Reviewed Original ResearchConceptsSupport vector machineRadial Basis Kernel Support Vector MachineKernel support vector machineCross-entropy errorSVM parameter optimizationUnseen test dataSVM kernel typesTraining dataVector machineEvolutionary algorithmGrid searchMean squared errorKernel typeMachineOptimization methodPrediction modelNumber of methodsParameter optimizationTest dataMedical applicationsOptimization parametersMortality prediction modelAlgorithmBest modelApplications
2005
Discrimination and calibration of mortality risk prediction models in interventional cardiology
Matheny M, Ohno-Machado L, Resnic F. Discrimination and calibration of mortality risk prediction models in interventional cardiology. Journal Of Biomedical Informatics 2005, 38: 367-375. PMID: 16198996, DOI: 10.1016/j.jbi.2005.02.007.Peer-Reviewed Original ResearchMeSH KeywordsAngioplasty, Balloon, CoronaryCalibrationCardiologyComorbidityDecision Support Systems, ClinicalDiagnosis, Computer-AssistedDiscriminant AnalysisExpert SystemsHumansIncidenceOutcome Assessment, Health CarePostoperative ComplicationsPrognosisRetrospective StudiesRisk AssessmentRisk FactorsROC CurveSurvival AnalysisSurvival RateUnited StatesConceptsLocal risk modelAcute myocardial infarctionHosmer-Lemeshow goodnessRisk prediction modelRisk factorsCardiology-National Cardiovascular Data RegistryConsecutive percutaneous coronary interventionsMortality risk prediction modelPercutaneous coronary interventionMultivariate risk factorsCertain risk factorsROC curveAccurate risk predictionIndividual casesGood discriminationCardiogenic shockHospital mortalityCoronary interventionUnstable anginaArtery interventionPatient populationMyocardial infarctionRisk modelElective proceduresWomen's HospitalA global goodness-of-fit test for receiver operating characteristic curve analysis via the bootstrap method
Zou K, Resnic F, Talos I, Goldberg-Zimring D, Bhagwat J, Haker S, Kikinis R, Jolesz F, Ohno-Machado L. A global goodness-of-fit test for receiver operating characteristic curve analysis via the bootstrap method. Journal Of Biomedical Informatics 2005, 38: 395-403. PMID: 16198998, DOI: 10.1016/j.jbi.2005.02.004.Peer-Reviewed Original ResearchAdolescentAdultAlgorithmsAngioplasty, Balloon, CoronaryBrain NeoplasmsCalibrationData Interpretation, StatisticalDecision Support Systems, ClinicalDiagnosis, Computer-AssistedDiscriminant AnalysisExpert SystemsFemaleHumansIncidenceMaleMiddle AgedOutcome Assessment, Health CarePrognosisRisk AssessmentRisk FactorsROC CurveSurvival AnalysisSurvival RateUnited States
2001
Vascular closure devices and the risk of vascular complications after percutaneous coronary intervention in patients receiving glycoprotein IIb-IIIa inhibitors
Resnic F, Blake G, Ohno-Machado L, Selwyn A, Popma J, Rogers C. Vascular closure devices and the risk of vascular complications after percutaneous coronary intervention in patients receiving glycoprotein IIb-IIIa inhibitors. The American Journal Of Cardiology 2001, 88: 493-496. PMID: 11524056, DOI: 10.1016/s0002-9149(01)01725-8.Peer-Reviewed Original ResearchMeSH KeywordsAge DistributionAgedAnalysis of VarianceAneurysm, FalseAngioplasty, Balloon, CoronaryAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedArteriovenous FistulaChi-Square DistributionCoronary DiseaseCoronary Vessel AnomaliesCoronary VesselsEquipment SafetyFemaleHematomaHumansIncidenceMaleMiddle AgedMultivariate AnalysisMyocardial InfarctionProbabilityRetrospective StudiesRisk AssessmentRisk FactorsSex DistributionConceptsPercutaneous coronary interventionVascular closure deviceGlycoprotein IIb-IIIa antagonistsVascular complication ratesVascular complicationsClosure deviceCoronary interventionComplication rateLower vascular complication ratesOverall vascular complication rateGlycoprotein IIb-IIIa inhibitorsIIb-IIIa inhibitorsSubgroup of patientsLength of stayHospital stayConsecutive patientsLarge hematomaSurgical repairArteriovenous fistulaPatient populationUnivariate analysisRetrospective analysisComplicationsPatient comfortPatients
1993
Prognostic classification for aids patients in Brazil
Ohno-Machado L. Prognostic classification for aids patients in Brazil. Journal Of Medical Systems 1993, 17: 163-172. PMID: 8254260, DOI: 10.1007/bf00996941.Peer-Reviewed Original ResearchMeSH KeywordsAcquired Immunodeficiency SyndromeAdolescentAdultAgedAIDS-Related Opportunistic InfectionsBrazilCause of DeathChildChild, PreschoolCross-Sectional StudiesDeveloping CountriesDiscriminant AnalysisFemaleHospitalizationHumansIncidenceInfantInfant, NewbornMaleMiddle AgedNeoplasmsSurvival RateConceptsHospitalized AIDS patientsPrognosis of deathHistory of transfusionGroup IV patientsNumber of infectionsEsophageal candidiasisIV patientsAIDS patientsFirst manifestationAID patientsRisk groupsPrognostic classificationPrognostic variablesSurvival ratePatientsFinal discriminant functionInfectionDiseaseDeathAnalysis groupHospitalizationTransfusionPrognosisGroupCandidiasis