2008
Validation of an Automated Safety Surveillance System with Prospective, Randomized Trial Data
Matheny M, Morrow D, Ohno-Machado L, Cannon C, Sabatine M, Resnic F. Validation of an Automated Safety Surveillance System with Prospective, Randomized Trial Data. Medical Decision Making 2008, 29: 247-256. PMID: 19015285, PMCID: PMC2743924, DOI: 10.1177/0272989x08327110.Peer-Reviewed Original ResearchMeSH KeywordsBayes TheoremData Interpretation, StatisticalDecision Support TechniquesFibrinolytic AgentsHumansIntracranial HemorrhagesMulticenter Studies as TopicMyocardial InfarctionRandomized Controlled Trials as TopicReproducibility of ResultsRetrospective StudiesSafety ManagementSentinel SurveillanceConceptsIntervention armMortality rateEvent ratesTrial BTrial AMajor bleeding ratesOutcomes Surveillance SystemIntracranial hemorrhage rateCumulative event rateRandomized trial dataEvent-rate analysisSafety surveillance systemSurveillance systemAdverse eventsMulticenter trialHemorrhage rateMonth 14Bleeding rateControl armClinical trialsTrial B.Trial dataTrialsObserved event ratesMonths
2007
Validating an automated outcomes surveillance application using data from a terminated randomized, controlled trial (OPUS [TIMI-16]).
Matheny M, Morrow D, Ohno-Machado L, Cannon C, Resnic F. Validating an automated outcomes surveillance application using data from a terminated randomized, controlled trial (OPUS [TIMI-16]). AMIA Annual Symposium Proceedings 2007, 1043. PMID: 18694141.Peer-Reviewed Original Research
2005
Monitoring Device Safety in Interventional Cardiology
Matheny M, Ohno-Machado L, Resnic F. Monitoring Device Safety in Interventional Cardiology. Journal Of The American Medical Informatics Association 2005, 13: 180-187. PMID: 16357356, PMCID: PMC1447549, DOI: 10.1197/jamia.m1908.Peer-Reviewed Original ResearchExploration of a Bayesian updating tool to provide real-time safety monitoring for new medical devices.
Matheny M, Ohno-Machado L, Resnic F. Exploration of a Bayesian updating tool to provide real-time safety monitoring for new medical devices. AMIA Annual Symposium Proceedings 2005, 2005: 1045. PMID: 16779332, PMCID: PMC1560574.Peer-Reviewed Original Research
2004
Exploration of a Bayesian Updating Methodology to Monitor the Safety of Interventional Cardiovascular Procedures
Resnic F, Zou K, Do D, Apostolakis G, Ohno-Machado L. Exploration of a Bayesian Updating Methodology to Monitor the Safety of Interventional Cardiovascular Procedures. Medical Decision Making 2004, 24: 399-407. PMID: 15271278, DOI: 10.1177/0272989x04267012.Peer-Reviewed Original ResearchMeSH KeywordsAtherectomy, CoronaryBayes TheoremEquipment SafetyHumansLikelihood FunctionsRetrospective StudiesConceptsConventional statistical methodsPrior probability distributionProbability distributionStatistical methodsBayesian updatingMedical device safety evaluationStable estimatesPatient risk groupsInterventional cardiology proceduresInterventional cardiovascular proceduresBayesianClinical outcomesPatient groupRotational atherectomyRisk groupsCardiovascular proceduresClinical practiceMethodologyCardiology proceduresEstimationEvent ratesSafety experienceEstimation of riskFrameworkNovel approachA greedy algorithm for supervised discretization
Butterworth R, Simovici D, Santos G, Ohno-Machado L. A greedy algorithm for supervised discretization. Journal Of Biomedical Informatics 2004, 37: 285-292. PMID: 15465481, DOI: 10.1016/j.jbi.2004.07.006.Peer-Reviewed Original Research
2001
Finding appropriate clinical trials: evaluating encoded eligibility criteria with incomplete data.
Ash N, Ogunyemi O, Zeng Q, Ohno-Machado L. Finding appropriate clinical trials: evaluating encoded eligibility criteria with incomplete data. AMIA Annual Symposium Proceedings 2001, 27-31. PMID: 11825151, PMCID: PMC2243370.Peer-Reviewed Original Research
1993
AIDS2: a decision-support tool for decreasing physicians' uncertainty regarding patient eligibility for HIV treatment protocols.
Ohno-Machado L, Parra E, Henry S, Tu S, Musen M. AIDS2: a decision-support tool for decreasing physicians' uncertainty regarding patient eligibility for HIV treatment protocols. AMIA Annual Symposium Proceedings 1993, 429-33. PMID: 8130510, PMCID: PMC2248545.Peer-Reviewed Original Research