2022
IMI-CDE: an interactive interface for collaborative mapping of study variables to common data elements
Tao S, Chou W, Li J, Du J, Ram P, Abeysinghe R, Xu H, Jiang X, Rose P, Ohno-Machado L, Zhang G. IMI-CDE: an interactive interface for collaborative mapping of study variables to common data elements. 2022, 00: 465-468. DOI: 10.1109/ichi54592.2022.00070.Peer-Reviewed Original Research
2017
User needs analysis and usability assessment of DataMed – a biomedical data discovery index
Dixit R, Rogith D, Narayana V, Salimi M, Gururaj A, Ohno-Machado L, Xu H, Johnson T. User needs analysis and usability assessment of DataMed – a biomedical data discovery index. Journal Of The American Medical Informatics Association 2017, 25: 337-344. PMID: 29202203, PMCID: PMC7378884, DOI: 10.1093/jamia/ocx134.Peer-Reviewed Original ResearchData discoveryUsability evaluationInformation needsUser interfaceBiomedical dataIterative usability evaluationsInformation retrieval toolsUser interface needsHigh-quality metadataResearchers informationCommon search enginesDiscovery systemRetrieval toolsDataMedUser studyRelevance judgmentsSearch enginesUser needsDataset explorationUsability assessmentRetrieval techniquesNew retrieval techniqueIncomplete metadataMetadataUsers
2014
Development of a Web Service for Analysis in a Distributed Network
Jiang X, Wu Y, Marsolo K, Ohno-Machado L. Development of a Web Service for Analysis in a Distributed Network. Healthcare 2014, 2: 1053. PMID: 25848586, PMCID: PMC4371401, DOI: 10.13063/2327-9214.1053.Peer-Reviewed Original ResearchWeb servicesCross-platform deploymentSoftware development processUser interface developmentNetwork security personnelUser interface designDevelopment processProject management systemGoogle CodeApache SubversionInterface developmentUser experiencePlatform deploymentSystem testingFunctional specificationManagement systemPotential usersSecurity personnelAlgorithm validationConcept proofDevelopment approachData analysisFeasibility of buildingModel constructionUsersChoosing blindly but wisely: differentially private solicitation of DNA datasets for disease marker discovery
Zhao Y, Wang X, Jiang X, Ohno-Machado L, Tang H. Choosing blindly but wisely: differentially private solicitation of DNA datasets for disease marker discovery. Journal Of The American Medical Informatics Association 2014, 22: 100-108. PMID: 25352565, PMCID: PMC4433380, DOI: 10.1136/amiajnl-2014-003043.Peer-Reviewed Original ResearchConceptsData ownersData usersHuman genomic datasetsHuman genomic dataPatient privacyPrivacyGeneration approachUsersData selectionReal dataDatasetGenomic datasetsPrivate solicitationDNA datasetsScientific discoveryNew approachGenomic dataHigh confidencePilot versionEvaluation methodRight choiceOwnersAlgorithmNew techniqueDisease marker discoveryPhenDisco: phenotype discovery system for the database of genotypes and phenotypes
Doan S, Lin K, Conway M, Ohno-Machado L, Hsieh A, Feupe S, Garland A, Ross M, Jiang X, Farzaneh S, Walker R, Alipanah N, Zhang J, Xu H, Kim H. PhenDisco: phenotype discovery system for the database of genotypes and phenotypes. Journal Of The American Medical Informatics Association 2014, 21: 31-36. PMID: 23989082, PMCID: PMC3912702, DOI: 10.1136/amiajnl-2013-001882.Peer-Reviewed Original ResearchConceptsNew information retrieval systemInformation retrieval systemsInformation retrieval toolsDatabase of GenotypesText processing toolsRetrieval systemSearch scenariosDiscovery systemRetrieval toolsAuthorized usersNon-standardized wayCross-study validationSearch comparisonProcessing toolsPromising performanceUsersPhenotype informationDatabaseInformationBiotechnology InformationQueriesMetadataEntrezResourcesSystem
2013
Detecting inappropriate access to electronic health records using collaborative filtering
Menon A, Jiang X, Kim J, Vaidya J, Ohno-Machado L. Detecting inappropriate access to electronic health records using collaborative filtering. Machine Learning 2013, 95: 87-101. PMID: 24683293, PMCID: PMC3967851, DOI: 10.1007/s10994-013-5376-1.Peer-Reviewed Original ResearchElectronic health recordsCollaborative filteringInappropriate accessHealth recordsSuspicious accessPrivacy policiesAccess patternsMachine learningManual auditingSecurity expertsLatent featuresAccess dataRecord accessHistorical dataSecurityFilteringUnrestricted accessFuture violationsAccessAudit processSVMUsersDatasetLearningAuditing
2010
DSGeo: Software tools for cross-platform analysis of gene expression data in GEO
Lacson R, Pitzer E, Kim J, Galante P, Hinske C, Ohno-Machado L. DSGeo: Software tools for cross-platform analysis of gene expression data in GEO. Journal Of Biomedical Informatics 2010, 43: 709-715. PMID: 20435161, PMCID: PMC2934864, DOI: 10.1016/j.jbi.2010.04.007.Peer-Reviewed Original ResearchConceptsAggregation of dataData loaderRelational databaseGene expression dataUser preferencesData browserData browsingCross-platform dataSoftware toolsSeamless integrationCross-platform analysisGroups of dataQueriesExpression dataPublic gene expression dataSpecific sample characteristicsLarge resourcesBrowserToolBrowsingAnnotatingUsersRetrievalApplicationsPlatform
2002
Visualization and evaluation of clusters for exploratory analysis of gene expression data
Kim J, Kohane I, Ohno-Machado L. Visualization and evaluation of clusters for exploratory analysis of gene expression data. Journal Of Biomedical Informatics 2002, 35: 25-36. PMID: 12415724, DOI: 10.1016/s1532-0464(02)00001-1.Peer-Reviewed Original ResearchConceptsClustering algorithmDifferent clustering algorithmsPopular clustering algorithmNew clustering algorithmComprehensive data visualizationGene expression data analysisData visualization strategiesExpression data analysisEvaluation of clustersData visualizationSoftware toolsCluster qualityCluster consistencyAlgorithmActual implementationData setsGene expression dataQuality measuresVisualizationPromising resultsFrameworkData analysisObjective evaluationUsersExpression data
1997
A virtual repository approach to clinical and utilization studies: application in mammography as alternative to a national database.
Ohno-Machado L, Boxwala A, Ehresman J, Smith D, Greenes R. A virtual repository approach to clinical and utilization studies: application in mammography as alternative to a national database. AMIA Annual Symposium Proceedings 1997, 369-73. PMID: 9357650, PMCID: PMC2233552.Peer-Reviewed Original ResearchConceptsMammography databaseVisualization of resultsHeterogeneous databasesFederated databasesCentralized architectureExploratory analysis toolLegacy systemsCommon queriesPrototype systemQueriesVirtual repositoryAlternative architecturesImmediate displayDifferent databasesArchitectureAnalysis toolsMammography dataUse of dataRepositoryMammography reportsDatabaseUsersDownloadSystemVisualization