2022
454: OBESITY IS NOT ASSOCIATED WITH INCREASED RISK OF ADVERSE TREATMENT OUTCOMES OR SERIOUS INFECTION IN INFLAMMATORY BOWEL DISEASES PATIENTS (IBD) STARTING NEW BIOLOGIC THERAPY
Gu P, Luo J, Paul P, Limketkai B, Sauk J, Park S, Parekh N, Zheng K, Rudrapatna V, Syal G, Ha C, Mcgovern D, Melmed G, Fleshner P, Eisenstein S, Ramamoorthy S, Dulai P, Boland B, Mahadevan U, Ohno-Machado L, Sandborn W, Singh S. 454: OBESITY IS NOT ASSOCIATED WITH INCREASED RISK OF ADVERSE TREATMENT OUTCOMES OR SERIOUS INFECTION IN INFLAMMATORY BOWEL DISEASES PATIENTS (IBD) STARTING NEW BIOLOGIC THERAPY. Gastroenterology 2022, 162: s-101-s-102. DOI: 10.1016/s0016-5085(22)60253-1.Peer-Reviewed Original Research
2021
Geographic Variation in Obesity at the State Level in the All of Us Research Program
Clark C, Chandler P, Zhou G, Noel N, Achilike C, Mendez L, O’Connor G, Smoller J, Weiss S, Murphy S, Ommerborn M, Karnes J, Klimentidis Y, Jordan C, Hiatt R, Ramirez A, Loperena R, Mayo K, Cohn E, Ohno-Machado L, Boerwinkle E, Cicek M, Schully S, Mockrin S, Gebo K, Karlson E. Geographic Variation in Obesity at the State Level in the All of Us Research Program. Preventing Chronic Disease 2021, 18: e104. PMID: 34941480, PMCID: PMC8718125, DOI: 10.5888/pcd18.210094.Peer-Reviewed Original ResearchConceptsBody mass indexObesity prevalenceElectronic health recordsSevere obesityPrevalence estimatesParticipants' electronic health recordsObesity prevention strategiesNational population-based estimatesEHR dataPopulation-based estimatesOverall obesity prevalenceState-level geographic variationsPopulation health studiesUS participantsEnrollment visitMass indexObesity preventionHigh prevalenceHealth StudyPrecision health approachObesityPrevention strategiesUs Research ProgramLarge geographic variationsCohort dataPediatric data from the All of Us research program: demonstration of pediatric obesity over time
Giangreco N, Lina S, Qian J, Kuoame A, Subbian V, Boerwinkle E, Cicek M, Clark C, Cohen E, Gebo K, Loperena-Cortes R, Mayo K, Mockrin S, Ohno-Machado L, Schully S, Tatonetti N, Ramirez A. Pediatric data from the All of Us research program: demonstration of pediatric obesity over time. JAMIA Open 2021, 4: ooab112. PMID: 35155998, PMCID: PMC8827025, DOI: 10.1093/jamiaopen/ooab112.Peer-Reviewed Original ResearchRacial, ethnic, and gender differences in obesity and body fat distribution: An All of Us Research Program demonstration project
Karnes J, Arora A, Feng J, Steiner H, Sulieman L, Boerwinkle E, Clark C, Cicek M, Cohn E, Gebo K, Loperena-Cortes R, Ohno-Machado L, Mayo K, Mockrin S, Ramirez A, Schully S, Klimentidis Y. Racial, ethnic, and gender differences in obesity and body fat distribution: An All of Us Research Program demonstration project. PLOS ONE 2021, 16: e0255583. PMID: 34358277, PMCID: PMC8345840, DOI: 10.1371/journal.pone.0255583.Peer-Reviewed Original ResearchConceptsBody mass indexBody fat distributionNon-Hispanic blacksNon-Hispanic whitesAlanine aminotransferaseNHB participantsFat distributionAge-adjusted obesity prevalenceNutrition Examination Survey dataBaseline physical examinationRace/ethnicityElectronic health recordsNHB womenWaist circumferenceMass indexHip ratioNHB menPhysical examinationNational HealthObesity prevalenceObesity ratesGender differencesObesityUs Research ProgramNHW participants
2018
Obesity Is Independently Associated With Higher Annual Burden and Costs of Hospitalization in Patients With Inflammatory Bowel Diseases
Nguyen N, Ohno-Machado L, Sandborn W, Singh S. Obesity Is Independently Associated With Higher Annual Burden and Costs of Hospitalization in Patients With Inflammatory Bowel Diseases. Clinical Gastroenterology And Hepatology 2018, 17: 709-718.e7. PMID: 30012429, DOI: 10.1016/j.cgh.2018.07.004.Peer-Reviewed Original ResearchConceptsNon-obese patientsInflammatory bowel diseaseNationwide Readmissions Database 2013Cost of hospitalizationBowel diseaseObese patientsAnnual burdenPropensity scoreHospitalization-related costsOutcomes of hospitalizationRepresentative cohort studyHigh-cost patientsCardiopulmonary complicationsIBD patientsAdjunctive therapyCohort studyIBD phenotypePreventable admissionsHigh burdenPatientsHospitalizationObesityAbstractTextObeseInconsistent associationsA Novel Stakeholder Engagement Approach for Patient-centered Outcomes Research
Kim K, Khodyakov D, Marie K, Taras H, Meeker D, Campos H, Ohno-Machado L. A Novel Stakeholder Engagement Approach for Patient-centered Outcomes Research. Medical Care 2018, 56: s41-s47. PMID: 30074950, PMCID: PMC6143220, DOI: 10.1097/mlr.0000000000000790.Peer-Reviewed Original ResearchConceptsClinical Data Research NetworkPatient-centered outcomes researchEngagement of patientsOutcomes research studiesConditions of focusStakeholder advisory boardPatient-centered outcomes research studiesKawasaki diseaseHeart failurePatient advocatesPatientsClinical sitesOutcomes researchSignificant differencesHealth researchCliniciansResearch NetworkResearch prioritiesSetting of prioritiesEngagement strategiesAdvisory BoardFavorable opinionObesityEngagement principlesDisease
2017
Obesity Is Associated With Higher Annual Burden and Costs of Hospitalization in Patients With Inflammatory Bowel Diseases: A Nationally Representative Cohort Study
Nguyen N, Ohno-Machado L, Sandborn W, Singh S. Obesity Is Associated With Higher Annual Burden and Costs of Hospitalization in Patients With Inflammatory Bowel Diseases: A Nationally Representative Cohort Study. The American Journal Of Gastroenterology 2017, 112: s345. DOI: 10.14309/00000434-201710001-00629.Peer-Reviewed Original Research