On the Dual Role of Carcinoembryonic Antigen‐Related Cell Adhesion Molecule 1 (CEACAM1) in Human Malignancies
Calinescu A, Turcu G, Nedelcu RI, Brinzea A, Hodorogea A, Antohe M, Diaconu C, Bleotu C, Pirici D, Jilaveanu LB, Ion DA, Badarau IA. On the Dual Role of Carcinoembryonic Antigen‐Related Cell Adhesion Molecule 1 (CEACAM1) in Human Malignancies. Journal Of Immunology Research 2018, 2018: 7169081. PMID: 30406153, PMCID: PMC6204181, DOI: 10.1155/2018/7169081.Peer-Reviewed Original ResearchConceptsCarcinoembryonic antigen-related cell adhesion molecule 1Cell adhesion molecule-1Adhesion molecule-1Molecule-1Role of CEACAM1Progression of malignancyPotential new molecular targetsNew molecular targetsPrognostic factorsSpecific cancer therapyPoor prognosisMetastatic spreadSolid cancersCarcinoembryonic antigenTumor progressionCarcinoembryonic antigen familyHuman malignanciesAntigen familyMolecular targetsCancer therapyBiologic functionsConsiderable downregulationMalignancyTumor suppressorEarly phase