2014
Feasibility of using an epigenetic marker of risk for lung cancer, methylation of p16, to promote smoking cessation among US veterans
Shofer S, Beyea M, Li S, Bastian LA, Wahidi MM, Kelley M, Lipkus IM. Feasibility of using an epigenetic marker of risk for lung cancer, methylation of p16, to promote smoking cessation among US veterans. BMJ Open Respiratory Research 2014, 1: e000032. PMID: 25478181, PMCID: PMC4212704, DOI: 10.1136/bmjresp-2014-000032.Peer-Reviewed Original ResearchLung cancer riskLung cancerSmoking cessationCancer riskMethylated p16Time of enrollmentAcceptance of testingCent of participantsAirway obstructionActive smokersCurrent smokersCessation assistanceTobacco exposureCessation ratesUS veteransEpigenetic markersSmokersMethylation of p16P16 methylationCancerP16SmokingEducational materialsRiskEducational presentations
2009
Responses to Online GSTM1 Genetic Test Results among Smokers Related to Patients with Lung Cancer: A Pilot Study
Sanderson SC, O'Neill SC, White DB, Bepler G, Bastian L, Lipkus IM, McBride CM. Responses to Online GSTM1 Genetic Test Results among Smokers Related to Patients with Lung Cancer: A Pilot Study. Cancer Epidemiology Biomarkers & Prevention 2009, 18: 1953-1961. PMID: 19567511, PMCID: PMC3417294, DOI: 10.1158/1055-9965.epi-08-0620.Peer-Reviewed Original ResearchConceptsSmoking cessation servicesLung cancer riskGenetic test resultsCessation servicesCancer riskLung cancerEffective smoking cessation servicesLower lung cancer riskPersonal genetic test resultsSignificant between-group differencesBetween-group differencesGenetic risk informationClinic settingSmokersSmokers' responsesCeiling effectsPilot studyGSTM1PatientsRiskCancerCessation-related cognitionsReal-time assessmentRisk informationFurther researchWhat Can Interest Tell Us about Uptake of Genetic Testing? Intention and Behavior amongst Smokers Related to Patients with Lung Cancer
Sanderson S, O’Neill S, Bastian L, Bepler G, McBride C. What Can Interest Tell Us about Uptake of Genetic Testing? Intention and Behavior amongst Smokers Related to Patients with Lung Cancer. Public Health Genomics 2009, 13: 116-124. PMID: 19556750, PMCID: PMC3696369, DOI: 10.1159/000226595.Peer-Reviewed Original ResearchConceptsLung cancer riskGenetic testingLung cancerGenetic testing intentionsCancer riskPsychosocial aspectsPositive attitudesChoices individualsLikert-style questionsTesting intentionsUntested assumptionsParticipantsHypothetical interestHypothetical scenariosMotivationBest predictorDaily Internet useTelephone surveySmokersIntentionPatientsAttitudesGenetic testsInternet useCancer
2005
Patients’ interest in discussing cancer risk and risk management with primary care physicians
Buchanan AH, Skinner CS, Rawl SM, Moser BK, Champion VL, Scott LL, Strigo TS, Bastian L. Patients’ interest in discussing cancer risk and risk management with primary care physicians. Patient Education And Counseling 2005, 57: 77-87. PMID: 15797155, DOI: 10.1016/j.pec.2004.04.003.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overCommunicationEducational StatusFemaleGenetic CounselingHealth Care SurveysHealth Knowledge, Attitudes, PracticeHealth Services Needs and DemandHumansLogistic ModelsMaleMass ScreeningMiddle AgedNeoplasmsNorth CarolinaPatient Acceptance of Health CarePatient Education as TopicPhysician-Patient RelationsPhysicians, FamilyPrimary PreventionRisk AssessmentRisk ManagementSurveys and QuestionnairesConceptsPrimary care physiciansCancer riskCancer genetic counselingCare physiciansCancer screening modalitiesGenetic counselingColon cancer screeningColon cancer riskEducation levelPhysician visitsCancer screeningPatient preferencesScreening modalityHigher education levelPatient interestTelephone surveyPhysiciansTamoxifenRiskMore participantsGreater proportionCounselingParticipantsHealthPatientsImpact of the Cancer Risk Intake System on Patient‐Clinician Discussions of Tamoxifen, Genetic Counseling, and Colonoscopy
Skinner CS, Rawl SM, Moser BK, Buchanan AH, Scott LL, Champion VL, Schildkraut JM, Parmigiani G, Clark S, Lobach DF, Bastian LA. Impact of the Cancer Risk Intake System on Patient‐Clinician Discussions of Tamoxifen, Genetic Counseling, and Colonoscopy. Journal Of General Internal Medicine 2005, 20: 360-365. PMID: 15857495, PMCID: PMC1490091, DOI: 10.1111/j.1525-1497.2005.40115.x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAlgorithmsAntineoplastic Agents, HormonalBreast NeoplasmsColonic NeoplasmsColonoscopyCommunicationCounselingFemaleGenetic CounselingHumansMaleMiddle AgedOdds RatioOvarian NeoplasmsPatient Acceptance of Health CarePatient Education as TopicPhysician-Patient RelationsPrimary Health CareRisk AssessmentTamoxifenConceptsPatient-clinician discussionsPrimary care settingCare settingsGenetic counselingBaseline telephone surveyObjective cancer riskMonths postvisitClinic visitsCancer riskTelephone surveyColonoscopySurvey 1TamoxifenPretest-posttest designGreater proportionComputerized programCounselingManagement recommendationsRisk management recommendationsParticipantsPostvisitFollowProportionSettingBaseline
2001
Women's Interest in Chemoprevention for Breast Cancer
Bastian L, Lipkus I, Kuchibhatla M, Weng H, Halabi S, Ryan P, Skinner C, Rimer B. Women's Interest in Chemoprevention for Breast Cancer. JAMA Internal Medicine 2001, 161: 1639-1644. PMID: 11434796, DOI: 10.1001/archinte.161.13.1639.Peer-Reviewed Original ResearchConceptsBreast cancer riskBreast cancerCancer riskGail scoreObjective breast cancer riskMammography decision aidObjective risk factorsDevelopment of cancerAbsolute riskRisk factorsChemopreventive agentsChemopreventionCancerComparative riskTelephone interviewsTamoxifen citrateDrugsWomenRiskNatural agentsCommunity sampleDecision aidScoresTherapyAgents