2023
Molecular Lithography on Silicon Wafers Guided by Porous, Extended Arrays of Small DNA Tiles
Mao D, Liu L, Zhang C, Liu H, Mao C. Molecular Lithography on Silicon Wafers Guided by Porous, Extended Arrays of Small DNA Tiles. Langmuir 2023, 39: 11782-11787. PMID: 37562139, DOI: 10.1021/acs.langmuir.3c01422.Peer-Reviewed Original ResearchConceptsE-beam lithographyDNA nanostructuresCost-effective fabrication methodSilicon wafersDNA origami structuresTile-based DNAMolecular lithographyCorresponding nanostructuresFabrication methodSmall DNA tilesNanostructuresFeature sizeLithographyOrigami structuresHF etchingDNA tilesWafersExtended arrayArrayLarge areasEtchingHereinSerial methodTemplateSizeSurface-assisted self-assembly of 2D, DNA binary crystals
Liu L, Mao D, Li Z, Zheng M, He K, Mao C. Surface-assisted self-assembly of 2D, DNA binary crystals. Nanoscale 2023, 15: 9941-9945. PMID: 37249191, DOI: 10.1039/d3nr01187a.Peer-Reviewed Original ResearchConceptsSolid surfaceTwo-dimensional nanoarraysDifferent adsorption strengthsComparable molecular weightAdsorption strengthDifferent tilesDifferential adsorptionComplicated nanostructuresMolar ratioMolecular weightBinary crystalsPowerful methodStructural complexityNanoarraysAdsorptionNanostructuresSurfaceEffective molar ratioHereinTile concentrations
2021
Kinetic DNA Self-Assembly: Simultaneously Co-folding Complementary DNA Strands into Identical Nanostructures
Zheng M, Li Z, Liu L, Li M, Paluzzi V, Choi J, Mao C. Kinetic DNA Self-Assembly: Simultaneously Co-folding Complementary DNA Strands into Identical Nanostructures. Journal Of The American Chemical Society 2021, 143: 20363-20367. PMID: 34808053, DOI: 10.1021/jacs.1c09925.Peer-Reviewed Original ResearchConceptsDNA nanostructuresAtomic force microscopy imagingLimited production yieldForce microscopy imagingLong DNA strandsComplementary DNA strandsDNA strandsDNA origamiEnzymatic reactionsIdentical nanostructuresNanostructuresLarge-scale productionDNA duplexConvenient methodInteraction kineticsMicroscopy imagingDuplex DNAComplementary strandSame solutionDNA origami
Dey S, Fan C, Gothelf K, Li J, Lin C, Liu L, Liu N, Nijenhuis M, Saccà B, Simmel F, Yan H, Zhan P. DNA origami. Nature Reviews Methods Primers 2021, 1: 13. DOI: 10.1038/s43586-020-00009-8.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsDNA origami technologyOrigami technologyDNA origami techniqueNear-atomic precisionDNA nanotechnologyOrigami techniqueDNA origamiDrug deliveryOrigami structuresMolecular machinesOrigami designBiological materialsLiving cellsSynthesisVivo synthesisNanophotonicsNanotechnologyNanofabricationNanostructuresNanoelectronicsBioimagingScale of productionFabricationTechnologyFunctionalization
2020
DNA Origami Post‐Processing by CRISPR‐Cas12a
Xiong Q, Xie C, Zhang Z, Liu L, Powell JT, Shen Q, Lin C. DNA Origami Post‐Processing by CRISPR‐Cas12a. Angewandte Chemie International Edition 2020, 59: 3956-3960. PMID: 31883145, PMCID: PMC7101258, DOI: 10.1002/anie.201915555.Peer-Reviewed Original ResearchConceptsDNA origami structuresCRISPR-Cas12aDNA origami devicesDNA origami designDNA origami techniqueNanomaterial fabricationFunctional nanodevicesDNA origamiScaffold strandTremendous promiseCutting-edge toolsVersatile toolNanodevicesNanostructuresFacileFabricationBiocompatibilityBiotechnologySequence specificityOrigamiEnzymatic methodMechanical propertiesStructural transformationDevicesIntricate structureDNA Origami Post‐Processing by CRISPR‐Cas12a
Xiong Q, Xie C, Zhang Z, Liu L, Powell J, Shen Q, Lin C. DNA Origami Post‐Processing by CRISPR‐Cas12a. Angewandte Chemie 2020, 132: 3984-3988. DOI: 10.1002/ange.201915555.Peer-Reviewed Original ResearchDNA origami structuresCRISPR-Cas12aDNA origami devicesDNA origami designDNA origami techniqueNanomaterial fabricationFunctional nanodevicesDNA origamiScaffold strandTremendous promiseCutting-edge toolsVersatile toolNanodevicesNanostructuresFacileFabricationBiocompatibilityBiotechnologySequence specificityOrigamiEnzymatic methodMechanical propertiesStructural transformationDevicesIntricate structure
2019
ATP-Triggered, Allosteric Self-Assembly of DNA Nanostructures
Li Q, Liu L, Mao D, Yu Y, Li W, Zhao X, Mao C. ATP-Triggered, Allosteric Self-Assembly of DNA Nanostructures. Journal Of The American Chemical Society 2019, 142: 665-668. PMID: 31877040, DOI: 10.1021/jacs.9b10272.Peer-Reviewed Original ResearchConceptsDNA nanostructuresVersatile molecular platformAptamer-ligand bindingResponsive assembliesSelf-AssemblyResponsive DNADrug deliveryResponsive behaviorATP aptamerMolecular machinesMolecular platformNanostructuresBiological systemsAllosteric mechanismBiosensingAssemblyAptamerGreat challengeConformationHereinPatterning Nanoparticles with DNA Molds
Liu L, Zheng M, Li Z, Li Q, Mao C. Patterning Nanoparticles with DNA Molds. ACS Applied Materials & Interfaces 2019, 11: 13853-13858. PMID: 30793605, DOI: 10.1021/acsami.8b22691.Peer-Reviewed Original ResearchConceptsSelf-assembled DNA nanostructuresAtomic force microscopyGold nanoparticlesNonspecific adsorptionDNA nanostructuresPatterned nanoparticlesForce microscopyNanoparticlesAccessible cavitiesSpecific recognitionStructural templateNanostructuresHexagonal arrayTemplateAdsorptionGeneral methodSubstrateDNA arraysHereinDNA templateFourier transform analysisMicroscopyArrayDirect interactionLarge array
2017
Regulating DNA Self‐assembly by DNA–Surface Interactions
Liu L, Li Y, Wang Y, Zheng J, Mao C. Regulating DNA Self‐assembly by DNA–Surface Interactions. ChemBioChem 2017, 18: 2404-2407. PMID: 29024338, DOI: 10.1002/cbic.201700545.Peer-Reviewed Original Research