Featured Publications
Cumulative Anticholinergic Exposure Is Associated with Poor Memory and Executive Function in Older Men
Han L, Agostini JV, Allore HG. Cumulative Anticholinergic Exposure Is Associated with Poor Memory and Executive Function in Older Men. Journal Of The American Geriatrics Society 2008, 56: 2203-2210. PMID: 19093918, PMCID: PMC3952110, DOI: 10.1111/j.1532-5415.2008.02009.x.Peer-Reviewed Original ResearchConceptsTotal anticholinergic burdenCumulative anticholinergic exposureOlder menAnticholinergic medicationsAnticholinergic burdenAnticholinergic exposureCumulative exposureVeterans Affairs primary care clinicsExecutive functionAnticholinergic medication useDeleterious adverse effectsProspective cohort studySeverity of hypertensionCommunity-dwelling menPrimary care clinicsDaily Living ScalePotential risk factorsPrescription of drugsAnticholinergic scoreCohort studyMultiple medicationsAnticholinergic effectsMedication useCare clinicsPhysical function
2011
Antidepressant Use and Cognitive Deficits in Older Men: Addressing Confounding by Indications with Different Methods
Han L, Kim N, Brandt C, Allore HG. Antidepressant Use and Cognitive Deficits in Older Men: Addressing Confounding by Indications with Different Methods. Annals Of Epidemiology 2011, 22: 9-16. PMID: 22037381, PMCID: PMC4054866, DOI: 10.1016/j.annepidem.2011.10.004.Peer-Reviewed Original ResearchConceptsDepression-related diagnosisAntidepressant useDepression symptomsOlder personsPropensity scoreHopkins Verbal Learning TestHypertensive menAntidepressant medicationIndication biasVerbal Learning TestMedical recordsPotential confoundingCumulative exposureOlder menCognitive impairmentMemory deficitsCognitive deficitsMultiple linear regressionLinear regressionLearning TestApparent associationScoresSymptomsDiagnosisIndications