2020
An integrated program of computer-presented and physical cognitive training exercises for children with attention-deficit/hyperactivity disorder
Wexler BE, Vitulano LA, Moore C, Katsovich L, Smith SD, Rush C, Grantz H, Dong J, Leckman JF. An integrated program of computer-presented and physical cognitive training exercises for children with attention-deficit/hyperactivity disorder. Psychological Medicine 2020, 51: 1524-1535. PMID: 32090720, DOI: 10.1017/s0033291720000288.Peer-Reviewed Original ResearchConceptsAttention deficit hyperactivity disorderExperimental medicine approachTAU groupMedicine approachHyperactivity disorderWeeks of treatmentCombined subtypeDiagnosis of ADHDClinical trial designHyperactive-impulsive subtypeAttention-deficit/hyperactivity disorderCross-over designDeficit hyperactivity disorderClinical improvementClinical symptomsRandomized crossCognitive dysfunctionCT groupPathophysiological heterogeneityCONSORT recommendationsTrial designResponse rateChange scoresSubtypesTargeted pathology
2011
Risperidone-Related Improvement of Irritability in Children with Autism Is not Associated with Changes in Serum of Epidermal Growth Factor and Interleukin-13
Tobiasova Z, van der Lingen KH, Scahill L, Leckman JF, Zhang Y, Chae W, McCracken JT, McDougle CJ, Vitiello B, Tierney E, Aman MG, Arnold LE, Katsovich L, Hoekstra PJ, Volkmar F, Bothwell AL, Kawikova I. Risperidone-Related Improvement of Irritability in Children with Autism Is not Associated with Changes in Serum of Epidermal Growth Factor and Interleukin-13. Journal Of Child And Adolescent Psychopharmacology 2011, 21: 555-564. PMID: 22070180, PMCID: PMC3279715, DOI: 10.1089/cap.2010.0134.Peer-Reviewed Original ResearchConceptsMedication-free subjectsEpidermal growth factorHealthy controlsInflammatory markersIL-13IL-1 receptor antagonistGrowth factorSerum inflammatory markersChemoattractant protein-1Placebo groupClinical improvementBaseline visitIL-17Serum levelsCytokine concentrationsInflammatory moleculesSerum concentrationsClinical trialsHealthy subjectsIL-1Interleukin-13RisperidoneAltered levelsProtein 1Diagnosis of autism