1986
A Parathyroid Hormone-Like Protein from Cultured Human Keratinocytes
Merendino JJ, Insogna KL, Milstone LM, Broadus AE, Stewart AF. A Parathyroid Hormone-Like Protein from Cultured Human Keratinocytes. Science 1986, 231: 388-390. PMID: 2417317, DOI: 10.1126/science.2417317.Peer-Reviewed Original ResearchConceptsHumoral hypercalcemiaParathyroid hormoneHuman keratinocytesParathyroid hormone receptor agonistsParathyroid hormone-like proteinSquamous epithelial originExtracts of tumorsHormone receptor agonistsHormone-like proteinHormone-like factorsAdenylate cyclase activityRat osteosarcoma cellsAdenylate cyclase productionNative parathyroid hormoneCultured human keratinocytesNormal human keratinocytesReceptor agonistMalignant tumorsCyclic adenosine monophosphateHypercalcemiaEpithelial originKeratinocyte-conditioned mediumMalignancyCyclase activityCyclase production
1983
GABA from putrescine is bound in macromolecular form in keratinocytes
Canellakis Z, Milstone L, Marsh L, Young P, Bondy P. GABA from putrescine is bound in macromolecular form in keratinocytes. Life Sciences 1983, 33: 599-603. PMID: 6192309, DOI: 10.1016/0024-3205(83)90247-3.Peer-Reviewed Original ResearchConceptsGamma-aminobutyric acidAcid-precipitable materialNeurotransmitter gamma-aminobutyric acidTotal cell-associated radioactivityTCA-precipitable radioactivityTCA-soluble radioactivityCultured human keratinocytesTCA-soluble fractionCell-associated radioactivityHuman foreskin keratinocytesTCA-precipitable materialAcid-soluble radioactivityRadioactive metabolitesSoluble radioactivityForeskin keratinocytesStratified culturesHuman keratinocytesKeratinocytesTrichloroacetic acidMacromolecular formRadioactivity